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Prion|February 27, 2009
Prion proteostasis: Hsp104 meets its supporting castElizabeth A Sweeny, James Shorter
Journal of Molecular Biology|November 27, 2015
Mechanistic and Structural Insights into the Prion-Disaggregase Activity of Hsp104Elizabeth A Sweeny, James Shorter
Journal of Visualized Experiments : Jove|October 13, 2011
Purification of hsp104, a protein disaggregaseElizabeth A Sweeny, Morgan E DeSantis, James Shorter
The Journal of Biological Chemistry|November 28, 2013
Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregationMorgan E Desantis, Elizabeth A Sweeny, David Snead, et al.
Nature Chemical Biology|November 17, 2009
A synergistic small-molecule combination directly eradicates diverse prion strain structuresBlake E Roberts, Martin L Duennwald, Huan Wang, et al.
Biochemistry|April 6, 2017
Avidity for Polypeptide Binding by Nucleotide-Bound Hsp104 StructuresClarissa L Weaver, Elizabeth C Duran, Korrie L Mack, et al.
Molecular Cell|January 27, 2015
The Hsp104 N-terminal domain enables disaggregase plasticity and potentiationElizabeth A Sweeny, Meredith E Jackrel, Michelle S Go, et al.
The Journal of Biological Chemistry|December 29, 2019
Structural and mechanistic insights into Hsp104 function revealed by synchrotron X-ray footprintingElizabeth A Sweeny, Amber Tariq, Esin Gurpinar, et al.
Neuro-Signals|December 22, 2007
Hsp104: a weapon to combat diverse neurodegenerative disordersJames Shorter
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