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Bioorganic & Medicinal Chemistry Letters|January 14, 2020
Emerging small-molecule therapeutic approaches for amyotrophic lateral sclerosis and frontotemporal dementiaDean G Brown, James Shorter, Heike J WobstThe Journal of Biological Chemistry|May 10, 2005
A cryptic Rab1-binding site in the p115 tethering proteinMatthew Beard, Ayano Satoh, James Shorter, et al.Biophysical Journal|April 7, 2019
AAA+ Protein-Based Technologies to Counter Neurodegenerative DiseaseZachary M March, Korrie L Mack, James ShorterBrain Research|March 22, 2016
Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative diseaseZachary M March, Oliver D King, James ShorterScience (New York, N.Y.)|June 17, 2017
Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104Stephanie N Gates, Adam L Yokom, JiaBei Lin, et al.Brain Research|March 27, 2012
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative diseaseOliver D King, Aaron D Gitler, James ShorterPlos Genetics|September 17, 2013
Hsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 modelMimi Cushman-Nick, Nancy M Bonini, James ShorterThe Journal of Biological Chemistry|November 4, 2021
N-alpha-acetylation of Huntingtin protein increases its propensity to aggregateLeah Gottlieb, Lin Guo, James Shorter, et al.Journal of Molecular Biology|August 31, 2021
Nuclear-Import Receptors Counter Deleterious Phase Transitions in Neurodegenerative DiseaseHana M Odeh, Charlotte M Fare, James ShorterPlos One|October 10, 2014
Suramin inhibits Hsp104 ATPase and disaggregase activityMariana P Torrente, Laura M Castellano, James ShorterPageof 20