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Current Opinion in Drug Discovery & Development
|
June 26, 2004
Structure-based generation of viable leads from small combinatorial libraries
Ellen R Laird, James F Blake
Biochemistry
|
June 26, 2002
Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain
Katherine E Fisher, Qing Fei, Ellen R Laird, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 8, 2012
Pyrazolopyridine inhibitors of B-Raf(V600E). Part 4: rational design and kinase selectivity profile of cell potent type II inhibitors
Steve Wenglowsky, David Moreno, Ellen R Laird, et al.
Future Medicinal Chemistry
|
November 13, 2013
5-alkyl-1,3-oxazole derivatives of 6-amino-nicotinic acids as alkyl ester bioisosteres are antagonists of the P2Y12 receptor
Peter Bach, Jonas Boström, Kay Brickmann, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 27, 2011
Potent and selective pyrazolo[1,5-a]pyrimidine based inhibitors of B-Raf(V600E) kinase with favorable physicochemical and pharmacokinetic properties
Li Ren, Ellen R Laird, Alex J Buckmelter, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 18, 2013
Imidazo[4,5-b]pyridine inhibitors of B-Raf kinase
Bradley J Newhouse, Steve Wenglowsky, Jonas Grina, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 3, 2007
Tetrazole and ester substituted tetrahydoquinoxalines as potent cholesteryl ester transfer protein inhibitors
C Todd Eary, Zachary S Jones, Robert D Groneberg, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 27, 2009
Novel N-substituted 2-phenyl-1-sulfonylamino-cyclopropane carboxylates as selective ADAMTS-5 (Aggrecanase-2) inhibitors
Makoto Shiozaki, Katsuya Maeda, Tomoya Miura, et al.
Biochemistry
|
March 19, 2003
Specificity determinants of human cathepsin s revealed by crystal structures of complexes
Thomas A Pauly, Traian Sulea, Mark Ammirati, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 8, 2011
The discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors
Alex J Buckmelter, Li Ren, Ellen R Laird, et al.
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of 4
Search research articles
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Showing results (1-10 of 32) with videos related to
Sort By:
Page
of 4
Current Opinion in Drug Discovery & Development
|
June 26, 2004
Structure-based generation of viable leads from small combinatorial libraries
Ellen R Laird, James F Blake
Biochemistry
|
June 26, 2002
Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain
Katherine E Fisher, Qing Fei, Ellen R Laird, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 8, 2012
Pyrazolopyridine inhibitors of B-Raf(V600E). Part 4: rational design and kinase selectivity profile of cell potent type II inhibitors
Steve Wenglowsky, David Moreno, Ellen R Laird, et al.
Future Medicinal Chemistry
|
November 13, 2013
5-alkyl-1,3-oxazole derivatives of 6-amino-nicotinic acids as alkyl ester bioisosteres are antagonists of the P2Y12 receptor
Peter Bach, Jonas Boström, Kay Brickmann, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 27, 2011
Potent and selective pyrazolo[1,5-a]pyrimidine based inhibitors of B-Raf(V600E) kinase with favorable physicochemical and pharmacokinetic properties
Li Ren, Ellen R Laird, Alex J Buckmelter, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 18, 2013
Imidazo[4,5-b]pyridine inhibitors of B-Raf kinase
Bradley J Newhouse, Steve Wenglowsky, Jonas Grina, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 3, 2007
Tetrazole and ester substituted tetrahydoquinoxalines as potent cholesteryl ester transfer protein inhibitors
C Todd Eary, Zachary S Jones, Robert D Groneberg, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 27, 2009
Novel N-substituted 2-phenyl-1-sulfonylamino-cyclopropane carboxylates as selective ADAMTS-5 (Aggrecanase-2) inhibitors
Makoto Shiozaki, Katsuya Maeda, Tomoya Miura, et al.
Biochemistry
|
March 19, 2003
Specificity determinants of human cathepsin s revealed by crystal structures of complexes
Thomas A Pauly, Traian Sulea, Mark Ammirati, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 8, 2011
The discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors
Alex J Buckmelter, Li Ren, Ellen R Laird, et al.
Page
of 4