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Nucleic Acid Therapeutics|July 18, 2024
mRNA Nuclear Clustering Leads to a Difference in Mutant Huntingtin mRNA and Protein Silencing by siRNAs <i>In Vivo</i>Sarah Allen, Daniel O'Reilly, Rachael Miller, et al.
The Journal of Cell Biology|September 13, 2022
Impaired XK recycling for importing manganese underlies striatal vulnerability in Huntington's diseaseGaurav Chhetri, Yuting Ke, Ping Wang, et al.
Neuroreport|October 11, 2008
A function of huntingtin in guanine nucleotide exchange on Rab11Xueyi Li, Ellen Sapp, Antonio Valencia, et al.
Journal of Huntington'S Disease|September 4, 2023
Levels of Synaptic Proteins in Brain and Neurofilament Light Chain in Cerebrospinal Fluid and Plasma of OVT73 Huntington's Disease Sheep Support a Prodromal Disease StateEllen Sapp, Adel Boudi, Suzanne J Reid, et al.
Bioconjugate Chemistry|May 3, 2017
Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable O-Phosphocholine-N-docosahexaenoyl-l-serine siRNA Conjugate in Mouse BrainMehran Nikan, Maire F Osborn, Andrew H Coles, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|June 26, 2018
Optimized Cholesterol-siRNA Chemistry Improves Productive Loading onto Extracellular VesiclesReka Agnes Haraszti, Rachael Miller, Marie-Cecile Didiot, et al.
Biorxiv : the Preprint Server for Biology|May 25, 2026
C57BL/6 BAC-CAG Huntington's disease mice show somatic CAG expansion and responses to small interfering RNAs comparable to the FVB strainJillian Belgrad, Ashley Summers, Samuel Hildebrand, et al.
Journal of Huntington'S Disease|April 4, 2014
Striatal synaptosomes from Hdh140Q/140Q knock-in mice have altered protein levels, novel sites of methionine oxidation, and excess glutamate release after stimulationAntonio Valencia, Ellen Sapp, Jeffrey S Kimm, et al.
Human Molecular Genetics|December 11, 2012
Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's diseaseAntonio Valencia, Ellen Sapp, Jeffrey S Kimm, et al.
Journal of Extracellular Vesicles|November 20, 2016
High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sourcesReka A Haraszti, Marie-Cecile Didiot, Ellen Sapp, et al.
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