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Nature Communications|June 23, 2016
ASC filament formation serves as a signal amplification mechanism for inflammasomesMathias S Dick, Lorenzo Sborgi, Sebastian Rühl, et al.Mbio|August 17, 2021
Guanylate-Binding Protein-Dependent Noncanonical Inflammasome Activation Prevents Burkholderia thailandensis-Induced Multinucleated Giant Cell FormationMarisa Dilucca, Saray Ramos, Kateryna Shkarina, et al.The Journal of Infectious Diseases|June 18, 2005
Protective anti-V antibodies inhibit Pseudomonas and Yersinia translocon assembly within host membranesJulien Goure, Petr Broz, Olivier Attree, et al.The EMBO Journal|February 24, 2024
NINJ1 induces plasma membrane rupture and release of damage-associated molecular pattern molecules during ferroptosisSaray Ramos, Ella Hartenian, José Carlos Santos, et al.Redox Biology|September 1, 2020
Electrophilic Nrf2 activators and itaconate inhibit inflammation at low dose and promote IL-1β production and inflammatory apoptosis at high doseJonathan Muri, Helene Wolleb, Petr Broz, et al.Nature Chemical Biology|July 17, 2012
Caspase-1 activity is required to bypass macrophage apoptosis upon Salmonella infectionAaron W Puri, Petr Broz, Aimee Shen, et al.Science (New York, N.Y.)|November 24, 2018
ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activationSebastian Rühl, Kateryna Shkarina, Benjamin Demarco, et al.European Journal of Immunology|December 24, 2017
The Gasdermin-D pore acts as a conduit for IL-1β secretion in miceRosalie Heilig, Mathias S Dick, Lorenzo Sborgi, et al.Proceedings of the National Academy of Sciences of the United States of America|November 21, 2023
Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in miceStefan A Fattinger, Luca Maurer, Petra Geiser, et al.Cell Host & Microbe|December 15, 2010
Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processingPetr Broz, Jakob von Moltke, Jonathan W Jones, et al.Pageof 13