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Molecular Carcinogenesis|June 21, 2019
Activation of Wnt signaling promotes olaparib resistant ovarian cancerTomomi M Yamamoto, Alexandra McMellen, Zachary L Watson, et al.Biorxiv : the Preprint Server for Biology|August 1, 2026
Abbapolin inhibitors of the PLK1 PBD as Prostate Cancer Therapeutics, in vivo activity and synergy with androgen therapyGeorge Merhej, Gurusankar Ramamoorthy, Danda Chapagai, et al.Scientific Reports|November 1, 2025
Pan-cancer Myc modulator that targets Myc-α-tubulin interaction to drive selective mitotic catastropheJessica Teitel, Margaret Farah, Michele L Dziubinski, et al.Biorxiv : the Preprint Server for Biology|February 23, 2026
ADT-030, a novel PDE10 inhibitor, demonstrates potent antitumor activity in pancreatic ductal adenocarcinomaDhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh, et al.Haematologica|October 15, 2020
Transducin β-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphomaYoussef Youssef, Vrajesh Karkhanis, Wing Keung Chan, et al.Cancer Prevention Research (Philadelphia, Pa.)|September 29, 2021
Suppression of Colon Tumorigenesis in Mutant Apc Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-CateninKevin J Lee, Wen-Chi L Chang, Xi Chen, et al.Science Translational Medicine|March 9, 2022
Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemiaLaura Barreyro, Avery M Sampson, Chiharu Ishikawa, et al.Biorxiv : the Preprint Server for Biology|February 8, 2024
A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI CancerJeremy B Foote, Tyler E Mattox, Adam B Keeton, et al.Cancer Research|December 19, 2024
A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal CancerJeremy B Foote, Tyler E Mattox, Adam B Keeton, et al.Pageof 4