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The Journal of Clinical Investigation|September 11, 2025
Targeting peroxiredoxin 2 prevents hepatocarcinogenesis in metabolic liver disease modelsEmilie Crouchet, Eugénie Schaeffer, Marine A Oudot, et al.Gut|March 29, 2020
Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinomaFrank Jühling, Nourdine Hamdane, Emilie Crouchet, et al.Gastroenterology|March 6, 2019
HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic ResponseNourdine Hamdane, Frank Jühling, Emilie Crouchet, et al.Journal of Hepatology|August 22, 2025
Claudin-1 is a mediator and therapeutic target in primary sclerosing cholangitisFabio Del Zompo, Emilie Crouchet, Tessa Ostyn, et al.Nature Communications|August 29, 2024
An atlas of the human liver diurnal transcriptome and its perturbation by hepatitis C virus infectionAtish Mukherji, Frank Jühling, Yogy Simanjuntak, et al.Science Translational Medicine|June 3, 2026
Claudin-1 targeting suppresses tumor growth, invasion, and metastasis in patient-derived cholangiocarcinoma modelsZeina Nehme, Marion Muller, Jade Brochon, et al.Nature Communications|February 19, 2025
A decision point between transdifferentiation and programmed cell death priming controls KRAS-dependent pancreatic cancer developmentAnne T Schneider, Christiane Koppe, Emilie Crouchet, et al.Science Translational Medicine|June 22, 2022
Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver diseaseNaoto Fujiwara, Naoto Kubota, Emilie Crouchet, et al.Journal of Hepatology|October 29, 2022
Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironmentNatascha Roehlen, Marion Muller, Zeina Nehme, et al.Science Translational Medicine|December 21, 2022
A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticityNatascha Roehlen, Antonio Saviano, Houssein El Saghire, et al.Pageof 4