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Nature Metabolism|July 23, 2020
Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight lossEmily A Day, Rebecca J Ford, Brennan K Smith, et al.Diabetes|August 25, 2016
Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1Brennan K Smith, Rebecca J Ford, Eric M Desjardins, et al.Nature Metabolism|October 15, 2024
Itaconate drives mtRNA-mediated type I interferon production through inhibition of succinate dehydrogenaseShane M O'Carroll, Christian G Peace, Juliana E Toller-Kawahisa, et al.Nature|October 31, 2024
Rhythmic IL-17 production by γδ T cells maintains adipose de novo lipogenesisAaron Douglas, Brenneth Stevens, Miguel Rendas, et al.Science Advances|March 7, 2025
Trained immunity causes myeloid cell hypercoagulabilityAisling M Rehill, Seán McCluskey, Anna E Ledwith, et al.Science Advances|January 22, 2025
Mitochondrial respiratory complex III sustains IL-10 production in activated macrophages and promotes tumor-mediated immune evasionAlessia Zotta, Juliana Toller-Kawahisa, Eva M Palsson-McDermott, et al.Nature Communications|August 28, 2021
The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissueBo Wang, Evangelia E Tsakiridis, Shuman Zhang, et al.Nature Metabolism|July 29, 2020
Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoformsStephen L Pinkosky, John W Scott, Eric M Desjardins, et al.Ebiomedicine|April 21, 2018
Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical ModelsRyan M Esquejo, Christopher T Salatto, Jake Delmore, et al.Nature|March 8, 2023
Macrophage fumarate hydratase restrains mtRNA-mediated interferon productionAlexander Hooftman, Christian G Peace, Dylan G Ryan, et al.Pageof 4