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Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 18, 2001
Combined three-dimensional quantitative structure-activity relationship analysis of cytochrome P450 2B6 substrates and protein homology modelingQinmi Wang, James R HalpertBiochemical and Biophysical Research Communications|August 30, 2005
Use of directed evolution of mammalian cytochromes P450 for investigating the molecular basis of enzyme function and generating novel biocatalystsSantosh Kumar, James R HalpertBiochimica Et Biophysica Acta|August 29, 2006
Structure-function analysis of cytochromes P450 2BYonghong Zhao, James R HalpertDrug Metabolism Reviews|September 6, 2007
Thermodynamics of ligand binding to P450 2B4 and P450eryF studied by isothermal titration calorimetryB K Muralidhara, James R HalpertChemical Research in Toxicology|June 18, 2002
7-Benzyloxyquinoline oxidation by P450eryF A245T: finding of a new fluorescent substrate probeKishore K Khan, James R HalpertCurrent Drug Metabolism|January 3, 2012
Plasticity of CYP2B enzymes: structural and solution biophysical methodsP Ross Wilderman, James R HalpertExpert Opinion on Drug Metabolism & Toxicology|December 2, 2008
Allosteric P450 mechanisms: multiple binding sites, multiple conformers or both?Dmitri R Davydov, James R HalpertProceedings of the National Academy of Sciences of the United States of America|October 18, 2003
An open conformation of mammalian cytochrome P450 2B4 at 1.6-A resolutionEmily E Scott, You Ai He, Michael R Wester, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 22, 2006
Engineering of cytochrome P450 3A4 for enhanced peroxide-mediated substrate oxidation using directed evolution and site-directed mutagenesisSantosh Kumar, Hong Liu, James R HalpertArchives of Biochemistry and Biophysics|December 5, 2002
Analysis of homotropic and heterotropic cooperativity of diazepam oxidation by CYP3A4 using site-directed mutagenesis and kinetic modelingYou Ai He, Fabienne Roussel, James R HalpertPageof 19