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Future Medicinal Chemistry|November 25, 2010
Structural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMRSean C Gay, Arthur G Roberts, James R HalpertJournal of Biomolecular Structure & Dynamics|June 8, 2012
Application of 3-Dimensional Homology Modeling of Cytochrome P450 2B1 for Interpretation of Site-Directed Mutagenesis ResultsGrazyna D Szklarz, Rick L Ornstein, James R HalpertBiochemistry|October 4, 2008
Allosteric transitions in cytochrome P450eryF explored with pressure-perturbation spectroscopy, lifetime FRET, and a novel fluorescent substrate, Fluorol-7GADmitri R Davydov, Nadezhda Y Davydova, James R HalpertThe Journal of Biological Chemistry|April 2, 2017
ω- <i>versus</i> (ω-1)-hydroxylation: Cytochrome P450 4B1 sterics make the callEmily E ScottJournal of Molecular Biology|February 5, 2008
Thermodynamic fidelity of the mammalian cytochrome P450 2B4 active site in binding substrates and inhibitorsB K Muralidhara, Ling Sun, Surendra Negi, et al.Archives of Biochemistry and Biophysics|October 10, 2006
Investigation of the role of cytochrome P450 2B4 active site residues in substrate metabolism based on crystal structures of the ligand-bound enzymeCynthia E Hernandez, Santosh Kumar, Hong Liu, et al.Biochemistry|December 8, 2017
Use of Phenoxyaniline Analogues To Generate Biochemical Insights into the Interactio n of Polybrominated Diphenyl Ether with CYP2B EnzymesChao Chen, Jingbao Liu, James R Halpert, et al.The Journal of Biological Chemistry|March 19, 2005
Directed evolution of mammalian cytochrome P450 2B1: mutations outside of the active site enhance the metabolism of several substrates, including the anticancer prodrugs cyclophosphamide and ifosfamideSantosh Kumar, Chong S Chen, David J Waxman, et al.Archives of Biochemistry and Biophysics|February 6, 2007
Role of subunit interactions in P450 oligomers in the loss of homotropic cooperativity in the cytochrome P450 3A4 mutant L211F/D214E/F304WHarshica Fernando, Dmitri R Davydov, Christopher C Chin, et al.Archives of Biochemistry and Biophysics|January 22, 2008
Effect of glutathione on homo- and heterotropic cooperativity in cytochrome P450 3A4Dmitri R Davydov, Nadezhda Y Davydova, Tamara N Tsalkova, et al.Pageof 19