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Nature Communications|February 25, 2026
Structural basis of the promiscuity of the unusual Fe(II) and 2-oxoglutarate dependent human aspartate/asparagine-β-hydroxylaseMariska de Munnik, Amelia Brasnett, Tiankun Zhou, et al.Nature Communications|February 10, 2021
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomesErna Davydova, Tadahiro Shimazu, Maren Kirstin Schuhmacher, et al.Cell Chemical Biology|March 7, 2017
Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma CellsAnthony Tumber, Andrea Nuzzi, Edward S Hookway, et al.Nature Cancer|April 18, 2024
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemiaHannah Lawson, James P Holt-Martyn, Vilma Dembitz, et al.Elife|February 21, 2022
Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosisChristopher J Brereton, Liudi Yao, Elizabeth R Davies, et al.Nature Communications|May 1, 2025
Filamin C dimerisation is regulated by HSPB7Zihao Wang, Guodong Cao, Miranda P Collier, et al.Chemical Science|November 11, 2021
Discovery of SARS-CoV-2 Mpro peptide inhibitors from modelling substrate and ligand bindingH T Henry Chan, Marc A Moesser, Rebecca K Walters, et al.Scientific Reports|June 25, 2021
Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19Martin A Redhead, C David Owen, Lennart Brewitz, et al.Cancer Research|April 6, 2021
JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate CancerAlec Paschalis, Jonathan Welti, Antje J Neeb, et al.Nature Chemical Biology|October 30, 2012
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humansWei Ge, Alexander Wolf, Tianshu Feng, et al.Pageof 59