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The Journal of Clinical Investigation|August 3, 2016
Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycinJianing Xu, Can G Pham, Steven K Albanese, et al.Cancer Medicine|August 16, 2014
The impact of genetic heterogeneity on biomarker development in kidney cancer assessed by multiregional samplingAlexander Sankin, Abraham A Hakimi, Nina Mikkilineni, et al.Nature Cell Biology|September 8, 2015
An interconnected hierarchical model of cell death regulation by the BCL-2 familyHui-Chen Chen, Masayuki Kanai, Akane Inoue-Yamauchi, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|April 27, 2013
Adverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators BAP1 and SETD2: a report by MSKCC and the KIRC TCGA research networkA Ari Hakimi, Irina Ostrovnaya, Boris Reva, et al.Cell Reports|August 17, 2022
Multiregional single-cell proteogenomic analysis of ccRCC reveals cytokine drivers of intratumor spatial heterogeneityNatalia Miheecheva, Ekaterina Postovalova, Yang Lyu, et al.The EMBO Journal|April 19, 2012
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1αDiego A Rodriguez, Sebastian Zamorano, Fernanda Lisbona, et al.JCO Precision Oncology|February 17, 2022
Persistent Severe Hyperlactatemia and Metabolic Derangement in Lethal <i>SDHB</i>-Mutated Metastatic Kidney Cancer: Clinical Challenges and Examples of Extreme Warburg EffectChung-Han Lee, Gunes Gundem, William Lee, et al.European Urology|October 6, 2012
Clinical and pathologic impact of select chromatin-modulating tumor suppressors in clear cell renal cell carcinomaA Ari Hakimi, Ying-Bei Chen, James Wren, et al.Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer|May 14, 2023
Combination Therapy With MDM2 and MEK Inhibitors Is Effective in Patient-Derived Models of Lung Adenocarcinoma With Concurrent Oncogenic Drivers and MDM2 AmplificationArielle Elkrief, Igor Odintsov, Vladimir Markov, et al.Cancer Cell|August 13, 2021
Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosisKosuke Tanaka, Helena A Yu, Shaoyuan Yang, et al.Pageof 6