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Molecular Therapy : the Journal of the American Society of Gene Therapy|June 6, 2021
Ligand conjugate SAR and enhanced delivery in NHPRichard James Holland, Kieu Lam, Xin Ye, et al.Nature Microbiology|September 28, 2016
Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNAEmily P Thi, Amy C H Lee, Joan B Geisbert, et al.Nature|April 23, 2015
Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primatesEmily P Thi, Chad E Mire, Amy C H Lee, et al.The Journal of Clinical Investigation|November 7, 2017
siRNA rescues nonhuman primates from advanced Marburg and Ravn virus diseaseEmily P Thi, Chad E Mire, Amy Ch Lee, et al.Viruses|March 28, 2024
Preclinical Antiviral and Safety Profiling of the HBV RNA Destabilizer AB-161Angela M Lam, Ravi R Dugyala, Muhammed Sheraz, et al.RSC Medicinal Chemistry|April 18, 2022
The identification of highly efficacious functionalised tetrahydrocyclopenta[c]pyrroles as inhibitors of HBV viral replication through modulation of HBV capsid assemblyAndrew G Cole, Steven G Kultgen, Nagraj Mani, et al.Journal of Medicinal Chemistry|September 4, 2024
Rational Design, Synthesis, and Structure-Activity Relationship of a Novel Isoquinolinone-Based Series of HBV Capsid Assembly Modulators Leading to the Identification of Clinical Candidate AB-836Andrew G Cole, Steven G Kultgen, Nagraj Mani, et al.ACS Medicinal Chemistry Letters|September 18, 2024
Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly ModulatorsEugen F Mesaros, Andrew G Cole, Steven G Kultgen, et al.Journal of Medicinal Chemistry|November 8, 2024
Structure-Activity Relationships and Discovery of (S)-5-(tert-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2',1':2,3]imidazo[4,5-h]quinoline-3-carboxylic Acid (AB-161), a Novel Orally Available and Liver-Centric HBV RNA DestabilizerDimitar Gotchev, Shuai Chen, Benjamin Dugan, et al.Nanomedicine : Nanotechnology, Biology, and Medicine|July 2, 2011
Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticlesFidel Martínez-Gutierrez, Emily P Thi, Judith M Silverman, et al.Pageof 3