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ACS Infectious Diseases|September 22, 2024
Control of Hepatitis B Virus with Imdusiran, a Small Interfering RNA TherapeuticEmily P Thi, Xin Ye, Nicholas M Snead, et al.
Bioorganic & Medicinal Chemistry Letters|August 26, 2023
Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506Andrew G Cole, Steven G Kultgen, Nagraj Mani, et al.
ACS Infectious Diseases|November 8, 2018
ARB-1740, a RNA Interference Therapeutic for Chronic Hepatitis B InfectionEmily P Thi, Ammen P Dhillon, Andrzej Ardzinski, et al.
Hepatology Communications|October 4, 2022
Safety, pharmacokinetics, and antiviral activity of the capsid inhibitor AB-506 from Phase 1 studies in healthy subjects and those with hepatitis BMan-Fung Yuen, Elina Berliba, Wattana Sukeepaisarnjaroen, et al.
Antiviral Research|September 26, 2024
Preclinical and clinical antiviral characterization of AB-836, a potent capsid assembly modulator against hepatitis B virusAngela M Lam, Nagraj Mani, Andrzej Ardzinski, et al.
Nature Communications|February 23, 2021
Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1Jang-June Park, Emily P Thi, Victor H Carpio, et al.
ACS Infectious Diseases|April 23, 2024
Discovery of C-Linked Nucleoside Analogues with Antiviral Activity against SARS-CoV-2Eugen F Mesaros, Benjamin J Dugan, Min Gao, et al.
The Lancet. Gastroenterology & Hepatology|May 22, 2026
The small interfering RNA imdusiran as single and multiple doses in healthy, randomised individuals and non-randomised individuals with chronic hepatitis B (AB-729-001): a phase 1a/b trialMan-Fung Yuen, Edward Gane, Jacinta A Holmes, et al.
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