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The EMBO Journal|January 27, 2006
Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switchMark A Guthridge, Jason A Powell, Emma F Barry, et al.
Mabs|July 4, 2018
The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunitiesUrmi Dhagat, Timothy R Hercus, Sophie E Broughton, et al.
Plos Biology|March 26, 2013
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survivalDaniel Thomas, Jason A Powell, Benjamin D Green, et al.
Science Advances|December 1, 2018
Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosisDenis Tvorogov, Daniel Thomas, Nicholas P D Liau, et al.
Nature Communications|January 28, 2018
A dual role for the N-terminal domain of the IL-3 receptor in cell signallingSophie E Broughton, Timothy R Hercus, Tracy L Nero, et al.
Cell Reports|July 22, 2014
Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibodySophie E Broughton, Timothy R Hercus, Matthew P Hardy, et al.
Blood|June 19, 2013
Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcriptionDaniel Thomas, Jason A Powell, Francois Vergez, et al.
Cancer Discovery|May 16, 2023
Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in LeukemiaWinnie L Kan, Urmi Dhagat, Kerstin B Kaufmann, et al.
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