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Elife
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December 7, 2017
Single-molecule studies contrast ordered DNA replication with stochastic translesion synthesis
Gengjing Zhao, Emma S Gleave, Meindert Hugo Lamers
Journal of Structural Biology
|
April 1, 2014
A structural analysis of the AAA+ domains in Saccharomyces cerevisiae cytoplasmic dynein
Emma S Gleave, Helgo Schmidt, Andrew P Carter
Nature Structural & Molecular Biology
|
March 20, 2012
Insights into dynein motor domain function from a 3.3-Å crystal structure
Helgo Schmidt, Emma S Gleave, Andrew P Carter
SLAS Discovery : Advancing Life Sciences R & D
|
November 29, 2024
High throughput application of the NanoBiT Biochemical Assay for the discovery of selective inhibitors of the interaction of PI3K-p110α with KRAS
Mohamed Ismail, Gareth Davies, Graham Sproat, et al.
Journal of Medicinal Chemistry
|
February 6, 2020
Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRAS<sup>G12C</sup>
Jason G Kettle, Sharan K Bagal, Sue Bickerton, et al.
Journal of Medicinal Chemistry
|
April 26, 2022
Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRAS<sup>G12C</sup>
Jason G Kettle, Sharan K Bagal, Sue Bickerton, et al.
Journal of Medicinal Chemistry
|
July 3, 2023
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS<sup>G12C</sup> with Demonstrable CNS Penetration
Jason G Kettle, Sharan K Bagal, Derek Barratt, et al.
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Search research articles
Search
Showing results (1-10 of 7) with videos related to
Sort By:
Page
of 1
Elife
|
December 7, 2017
Single-molecule studies contrast ordered DNA replication with stochastic translesion synthesis
Gengjing Zhao, Emma S Gleave, Meindert Hugo Lamers
Journal of Structural Biology
|
April 1, 2014
A structural analysis of the AAA+ domains in Saccharomyces cerevisiae cytoplasmic dynein
Emma S Gleave, Helgo Schmidt, Andrew P Carter
Nature Structural & Molecular Biology
|
March 20, 2012
Insights into dynein motor domain function from a 3.3-Å crystal structure
Helgo Schmidt, Emma S Gleave, Andrew P Carter
SLAS Discovery : Advancing Life Sciences R & D
|
November 29, 2024
High throughput application of the NanoBiT Biochemical Assay for the discovery of selective inhibitors of the interaction of PI3K-p110α with KRAS
Mohamed Ismail, Gareth Davies, Graham Sproat, et al.
Journal of Medicinal Chemistry
|
February 6, 2020
Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRAS<sup>G12C</sup>
Jason G Kettle, Sharan K Bagal, Sue Bickerton, et al.
Journal of Medicinal Chemistry
|
April 26, 2022
Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRAS<sup>G12C</sup>
Jason G Kettle, Sharan K Bagal, Sue Bickerton, et al.
Journal of Medicinal Chemistry
|
July 3, 2023
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS<sup>G12C</sup> with Demonstrable CNS Penetration
Jason G Kettle, Sharan K Bagal, Derek Barratt, et al.
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of 1