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SLAS Discovery : Advancing Life Sciences R & D
|
February 29, 2020
The Impact of Variable Selection Coverage on Detection of Ligands from a DNA-Encoded Library Screen
Kelly A McCarthy, G Joseph Franklin, David R Lancia, et al.
Elife
|
January 6, 2016
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
Andrew R Conery, Richard C Centore, Adrianne Neiss, et al.
Targeted Oncology
|
February 24, 2023
FT-6876, a Potent and Selective Inhibitor of CBP/p300, is Active in Preclinical Models of Androgen Receptor-Positive Breast Cancer
Maureen Caligiuri, Grace L Williams, Jennifer Castro, et al.
Journal of Medicinal Chemistry
|
April 9, 2026
Nanoscale Direct-to-Biology Optimization of Cdk2 Inhibitors
James L Douthwaite, Damian J Houde, Eneida Pardo, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 9, 2015
Development of methyl isoxazoleazepines as inhibitors of BET
Michael C Hewitt, Yves Leblanc, Victor S Gehling, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains
Alexander M Taylor, Rishi G Vaswani, Victor S Gehling, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 14, 2017
Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance
Terry D Crawford, Steffan Vartanian, Alexandre Côté, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors
Victor S Gehling, Michael C Hewitt, Rishi G Vaswani, et al.
Journal of Medicinal Chemistry
|
January 28, 2016
Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials
Brian K Albrecht, Victor S Gehling, Michael C Hewitt, et al.
Journal of Medicinal Chemistry
|
October 6, 2018
GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like
Shumei Wang, Vickie Tsui, Terry D Crawford, et al.
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Search research articles
Search
Showing results (1-10 of 15) with videos related to
Sort By:
Page
of 2
SLAS Discovery : Advancing Life Sciences R & D
|
February 29, 2020
The Impact of Variable Selection Coverage on Detection of Ligands from a DNA-Encoded Library Screen
Kelly A McCarthy, G Joseph Franklin, David R Lancia, et al.
Elife
|
January 6, 2016
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
Andrew R Conery, Richard C Centore, Adrianne Neiss, et al.
Targeted Oncology
|
February 24, 2023
FT-6876, a Potent and Selective Inhibitor of CBP/p300, is Active in Preclinical Models of Androgen Receptor-Positive Breast Cancer
Maureen Caligiuri, Grace L Williams, Jennifer Castro, et al.
Journal of Medicinal Chemistry
|
April 9, 2026
Nanoscale Direct-to-Biology Optimization of Cdk2 Inhibitors
James L Douthwaite, Damian J Houde, Eneida Pardo, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 9, 2015
Development of methyl isoxazoleazepines as inhibitors of BET
Michael C Hewitt, Yves Leblanc, Victor S Gehling, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains
Alexander M Taylor, Rishi G Vaswani, Victor S Gehling, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 14, 2017
Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance
Terry D Crawford, Steffan Vartanian, Alexandre Côté, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors
Victor S Gehling, Michael C Hewitt, Rishi G Vaswani, et al.
Journal of Medicinal Chemistry
|
January 28, 2016
Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials
Brian K Albrecht, Victor S Gehling, Michael C Hewitt, et al.
Journal of Medicinal Chemistry
|
October 6, 2018
GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like
Shumei Wang, Vickie Tsui, Terry D Crawford, et al.
Page
of 2