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Research Square|January 10, 2024
Antigen experience history directs distinct functional states of CD8+ CAR T cells during the anti-leukemia responseKole R DeGolier, Etienne Danis, Marc D'Antonio, et al.Cytotherapy|October 17, 2022
Digital polymerase chain reaction strategies for accurate and precise detection of vector copy number in chimeric antigen receptor T-cell productsLindsey A Murphy, Russell C Marians, Kristen Miller, et al.Nature Immunology|January 2, 2025
Antigen experience history directs distinct functional states of CD8<sup>+</sup> CAR T cells during the antileukemia responseKole R DeGolier, Etienne Danis, Marc D'Antonio, et al.Molecular Therapy. Oncology|May 7, 2025
Characterization of a multiplex digital PCR assay to quantify total T cells relative to chimeric antigen receptor-positive T cellsLindsey A Murphy, Laura Sedivy, M Eric Kohler, et al.Science Translational Medicine|November 24, 2017
TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearanceYinmeng Yang, M Eric Kohler, Christopher D Chien, et al.Journal for Immunotherapy of Cancer|April 17, 2025
T-bet overexpression enhances CAR T cell effector functions and antigen sensitivityJennifer M Cimons, Kole R DeGolier, Samuel D Burciaga, et al.Cancer Cell|March 11, 2025
Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemiaCatherine Pham-Danis, Amanda J Novak, Etienne Danis, et al.Blood|September 14, 2018
Murine pre-B-cell ALL induces T-cell dysfunction not fully reversed by introduction of a chimeric antigen receptorHaiying Qin, Kazusa Ishii, Sang Nguyen, et al.Haematologica|August 11, 2022
Potent preclinical activity of FLT3-directed chimeric antigen receptor T-cell immunotherapy against <i>FLT3</i>- mutant acute myeloid leukemia and <i>KMT2A</i>-rearranged acute lymphoblastic leukemiaLisa M Niswander, Zachary T Graff, Christopher D Chien, et al.Journal of Immunology (Baltimore, Md. : 1950)|February 28, 2024
Granzyme F: Exhaustion Marker and Modulator of Chimeric Antigen Receptor T Cell-Mediated CytotoxicityZachary L Z Hay, Dale D Kim, Jennifer M Cimons, et al.Pageof 3