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Epilepsy Currents|November 25, 2020
The Role of the Persistent Sodium Current in EpilepsyEric R Wengert, Manoj K Patel
Neuropharmacology|July 7, 2019
Prax330 reduces persistent and resurgent sodium channel currents and neuronal hyperexcitability of subiculum neurons in a mouse model of SCN8A epileptic encephalopathyEric R Wengert, Anusha U Saga, Payal S Panchal, et al.
Biorxiv : the Preprint Server for Biology|March 11, 2024
Parvalbumin Interneuron Impairment Leads to Synaptic Transmission Deficits and Seizures in SCN8A Epileptic EncephalopathyRaquel M Miralles, Alexis R Boscia, Shrinidhi Kittur, et al.
Epilepsia Open|November 26, 2021
Astrocyte reactivity in a mouse model of SCN8A epileptic encephalopathyJeremy A Thompson, Raquel M Miralles, Eric R Wengert, et al.
Frontiers in Neuroscience|March 25, 2021
Adrenergic Mechanisms of Audiogenic Seizure-Induced Death in a Mouse Model of SCN8A EncephalopathyEric R Wengert, Ian C Wenker, Elizabeth L Wagner, et al.
Brain Research|November 29, 2021
Targeted Augmentation of Nuclear Gene Output (TANGO) of Scn1a rescues parvalbumin interneuron excitability and reduces seizures in a mouse model of Dravet SyndromeEric R Wengert, Pravin K Wagley, Samantha M Strohm, et al.
Epilepsia|May 22, 2018
The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathyErin M Baker, Christopher H Thompson, Nicole A Hawkins, et al.
Human Mutation|May 5, 2018
Partial loss-of-function of sodium channel SCN8A in familial isolated myoclonusJacy L Wagnon, Niccolò E Mencacci, Bryan S Barker, et al.
JCI Insight|October 22, 2024
Parvalbumin interneuron impairment causes synaptic transmission deficits and seizures in SCN8A developmental and epileptic encephalopathyRaquel M Miralles, Alexis R Boscia, Shrinidhi Kittur, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|September 21, 2021
Somatostatin-Positive Interneurons Contribute to Seizures in SCN8A Epileptic EncephalopathyEric R Wengert, Raquel M Miralles, Kyle C A Wedgwood, et al.
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