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Bioorganic & Medicinal Chemistry Letters
|
March 13, 2010
Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors
Michael S Malamas, Keith Barnes, Yu Hui, et al.
Journal of the American Chemical Society
|
November 19, 2004
Structure-based design of estrogen receptor-beta selective ligands
Eric S Manas, Rayomand J Unwalla, Zhang B Xu, et al.
Bioorganic & Medicinal Chemistry
|
October 20, 2009
Dual acting norepinephrine reuptake inhibitors and 5-HT(2A) receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles
Gavin D Heffernan, Richard D Coghlan, Eric S Manas, et al.
Journal of Medicinal Chemistry
|
December 10, 2016
Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA<sub>2</sub>)
Alison J-A Woolford, Philip J Day, Véronique Bénéton, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 11, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1' substrate binding pocket
Lee D Jennings, Derek C Cole, Joseph R Stock, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 29, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets
Derek C Cole, Joseph R Stock, Rajiv Chopra, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 5, 2009
Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent beta-secretase (BACE1) inhibitors
Pawel Nowak, Derek C Cole, Ann Aulabaugh, et al.
Journal of Medicinal Chemistry
|
October 13, 2006
Acylguanidines as small-molecule beta-secretase inhibitors
Derek C Cole, Eric S Manas, Joseph R Stock, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 9, 2008
Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors
Krista B Goodman, Michael J Bury, Mui Cheung, et al.
Journal of Medicinal Chemistry
|
May 12, 2016
Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening
Alison J-A Woolford, Joseph E Pero, Sridhar Aravapalli, et al.
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Search research articles
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Showing results (21-30 of 30) with videos related to
Sort By:
Page
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You have reached the last page of results.
This site can display upto 30 results.
Bioorganic & Medicinal Chemistry Letters
|
March 13, 2010
Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors
Michael S Malamas, Keith Barnes, Yu Hui, et al.
Journal of the American Chemical Society
|
November 19, 2004
Structure-based design of estrogen receptor-beta selective ligands
Eric S Manas, Rayomand J Unwalla, Zhang B Xu, et al.
Bioorganic & Medicinal Chemistry
|
October 20, 2009
Dual acting norepinephrine reuptake inhibitors and 5-HT(2A) receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles
Gavin D Heffernan, Richard D Coghlan, Eric S Manas, et al.
Journal of Medicinal Chemistry
|
December 10, 2016
Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA<sub>2</sub>)
Alison J-A Woolford, Philip J Day, Véronique Bénéton, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 11, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1' substrate binding pocket
Lee D Jennings, Derek C Cole, Joseph R Stock, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 29, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets
Derek C Cole, Joseph R Stock, Rajiv Chopra, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 5, 2009
Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent beta-secretase (BACE1) inhibitors
Pawel Nowak, Derek C Cole, Ann Aulabaugh, et al.
Journal of Medicinal Chemistry
|
October 13, 2006
Acylguanidines as small-molecule beta-secretase inhibitors
Derek C Cole, Eric S Manas, Joseph R Stock, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 9, 2008
Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors
Krista B Goodman, Michael J Bury, Mui Cheung, et al.
Journal of Medicinal Chemistry
|
May 12, 2016
Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening
Alison J-A Woolford, Joseph E Pero, Sridhar Aravapalli, et al.
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of 3