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JCI Insight|February 8, 2022
Regional variability and genotypic and pharmacodynamic effects on PrP concentration in the CNSMeredith A Mortberg, Hien T Zhao, Andrew G Reidenbach, et al.
JCI Insight|July 31, 2019
Antisense oligonucleotides extend survival of prion-infected miceGregory J Raymond, Hien Tran Zhao, Brent Race, et al.
Brain Communications|May 26, 2025
Evidence that minocycline treatment confounds the interpretation of neurofilament as a biomarkerJuliana E Gentile, Christina N Heiss, Taylor L Corridon, et al.
Nucleic Acids Research|August 11, 2020
Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpointsEric Vallabh Minikel, Hien T Zhao, Jason Le, et al.
Plos Pathogens|May 26, 2026
PrP turnover in vivo and the time to effect of prion disease therapeuticsTaylor L Corridon, Jill O'Moore, Alyssa Seerley, et al.
Nature Medicine|January 14, 2025
In vivo base editing extends lifespan of a humanized mouse model of prion diseaseMeirui An, Jessie R Davis, Jonathan M Levy, et al.
Biorxiv : the Preprint Server for Biology|March 23, 2026
Divalent siRNA for prion diseaseJuliana E Gentile, Taylor L Corridon, Fiona E Serack, et al.
Nucleic Acids Research|April 25, 2026
Divalent siRNA for prion diseaseJuliana E Gentile, Taylor L Corridon, Fiona E Serack, et al.
Neurology|June 8, 2019
Age at onset in genetic prion disease and the design of preventive clinical trialsEric Vallabh Minikel, Sonia M Vallabh, Margaret C Orseth, et al.
The Journal of Biological Chemistry|July 30, 2020
Multimodal small-molecule screening for human prion protein bindersAndrew G Reidenbach, Michael F Mesleh, Dominick Casalena, et al.
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