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Nature Communications|June 21, 2026
A unified platform for the rapid assembly of glutarimides for Cereblon E3 ligase modulatory drugsDavid M Whalley, Olivier Lorthioir, Niall A Anderson, et al.Journal of Medicinal Chemistry|May 21, 2024
Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion MutationsClare Thomson, Peter Barton, Erin Braybrooke, et al.Journal of Medicinal Chemistry|August 12, 2024
Accelerated Discovery of Carbamate Cbl-b Inhibitors Using Generative AI Models and Structure-Based Drug DesignTaylor R Quinn, Kathryn A Giblin, Clare Thomson, et al.Journal of Medicinal Chemistry|September 28, 2024
Optimization of Potent, Efficacious, Selective and Blood-Brain Barrier Penetrating Inhibitors Targeting EGFR Exon20 Insertion MutationsClare Thomson, Erin Braybrooke, Nicola Colclough, et al.Journal of Medicinal Chemistry|January 27, 2025
Highly Optimized CNS Penetrant Inhibitors of EGFR Exon20 Insertion MutationsWilliam McCoull, Clare Thomson, Erin Braybrooke, et al.Journal of Medicinal Chemistry|July 3, 2023
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS<sup>G12C</sup> with Demonstrable CNS PenetrationJason G Kettle, Sharan K Bagal, Derek Barratt, et al.Pageof 1