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Nature
|
February 11, 2026
CSN5i-3 is an orthosteric molecular glue inhibitor of COP9 signalosome
Huigang Shi, Xiaorong Wang, Clinton Yu, et al.
Microbiology Spectrum
|
March 11, 2026
<i>In vitro</i> activity of MRS-2541, a novel MetRS inhibitor, against a selection of resistant gram-positive organisms associated with serious hospital infections
John Domagala, Seyedhameneh Jahanbakhsh, Angela K Mendez, et al.
The Journal of Infectious Diseases
|
October 15, 2016
A Novel Calcium-Dependent Kinase Inhibitor, Bumped Kinase Inhibitor 1517, Cures Cryptosporidiosis in Immunosuppressed Mice
Alejandro Castellanos-Gonzalez, Hayley Sparks, Samantha Nava, et al.
Antimicrobial Agents and Chemotherapy
|
August 7, 2015
In Vitro and In Vivo Effects of the Bumped Kinase Inhibitor 1294 in the Related Cyst-Forming Apicomplexans Toxoplasma gondii and Neospora caninum
Pablo Winzer, Joachim Müller, Adriana Aguado-Martínez, et al.
Journal of Structural Biology
|
May 5, 2010
The structure of tryptophanyl-tRNA synthetase from Giardia lamblia reveals divergence from eukaryotic homologs
Tracy L Arakaki, Megan Carter, Alberto J Napuli, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 4, 2017
Optimization of a binding fragment targeting the "enlarged methionine pocket" leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors
Wenlin Huang, Zhongsheng Zhang, Ranae M Ranade, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
August 8, 2015
A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens
Cho Yeow Koh, Latha Kallur Siddaramaiah, Ranae M Ranade, et al.
Structure (London, England : 1993)
|
August 21, 2012
Distinct states of methionyl-tRNA synthetase indicate inhibitor binding by conformational selection
Cho Yeow Koh, Jessica E Kim, Sayaka Shibata, et al.
The Journal of Antimicrobial Chemotherapy
|
February 4, 2020
Methionyl-tRNA synthetase inhibitor has potent in vivo activity in a novel Giardia lamblia luciferase murine infection model
Samantha A Michaels, Han-Wei Shih, Bailin Zhang, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 27, 2016
5-Aminopyrazole-4-carboxamide analogues are selective inhibitors of Plasmodium falciparum microgametocyte exflagellation and potential malaria transmission blocking agents
Wenlin Huang, Matthew A Hulverson, Zhongsheng Zhang, et al.
Page
of 11
Search research articles
Search
Showing results (41-50 of 108) with videos related to
Sort By:
Page
of 11
Nature
|
February 11, 2026
CSN5i-3 is an orthosteric molecular glue inhibitor of COP9 signalosome
Huigang Shi, Xiaorong Wang, Clinton Yu, et al.
Microbiology Spectrum
|
March 11, 2026
<i>In vitro</i> activity of MRS-2541, a novel MetRS inhibitor, against a selection of resistant gram-positive organisms associated with serious hospital infections
John Domagala, Seyedhameneh Jahanbakhsh, Angela K Mendez, et al.
The Journal of Infectious Diseases
|
October 15, 2016
A Novel Calcium-Dependent Kinase Inhibitor, Bumped Kinase Inhibitor 1517, Cures Cryptosporidiosis in Immunosuppressed Mice
Alejandro Castellanos-Gonzalez, Hayley Sparks, Samantha Nava, et al.
Antimicrobial Agents and Chemotherapy
|
August 7, 2015
In Vitro and In Vivo Effects of the Bumped Kinase Inhibitor 1294 in the Related Cyst-Forming Apicomplexans Toxoplasma gondii and Neospora caninum
Pablo Winzer, Joachim Müller, Adriana Aguado-Martínez, et al.
Journal of Structural Biology
|
May 5, 2010
The structure of tryptophanyl-tRNA synthetase from Giardia lamblia reveals divergence from eukaryotic homologs
Tracy L Arakaki, Megan Carter, Alberto J Napuli, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 4, 2017
Optimization of a binding fragment targeting the "enlarged methionine pocket" leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors
Wenlin Huang, Zhongsheng Zhang, Ranae M Ranade, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
August 8, 2015
A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens
Cho Yeow Koh, Latha Kallur Siddaramaiah, Ranae M Ranade, et al.
Structure (London, England : 1993)
|
August 21, 2012
Distinct states of methionyl-tRNA synthetase indicate inhibitor binding by conformational selection
Cho Yeow Koh, Jessica E Kim, Sayaka Shibata, et al.
The Journal of Antimicrobial Chemotherapy
|
February 4, 2020
Methionyl-tRNA synthetase inhibitor has potent in vivo activity in a novel Giardia lamblia luciferase murine infection model
Samantha A Michaels, Han-Wei Shih, Bailin Zhang, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 27, 2016
5-Aminopyrazole-4-carboxamide analogues are selective inhibitors of Plasmodium falciparum microgametocyte exflagellation and potential malaria transmission blocking agents
Wenlin Huang, Matthew A Hulverson, Zhongsheng Zhang, et al.
Page
of 11