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Frontiers in Molecular Neuroscience|June 7, 2014
LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complexMaria D Cirnaru, Antonella Marte, Elisa Belluzzi, et al.Cellular and Molecular Life Sciences : CMLS|June 12, 2023
Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathologyDean Paes, Melissa Schepers, Emily Willems, et al.Neurobiology of Disease|July 6, 2025
The complex phenotype and function of spinal cord microglia during ALS progression and the impact of metabotropic glutamate receptor type 5 down-regulation in SOD1<sup>G93A</sup> miceMatilde Balbi, Carola Torazza, Tiziana Altosole, et al.European Journal of Medicinal Chemistry|August 26, 2016
New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairmentChiara Brullo, Roberta Ricciarelli, Jos Prickaerts, et al.Brain, Behavior, and Immunity|December 30, 2022
Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosisMelissa Schepers, Dean Paes, Assia Tiane, et al.Pageof 6