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Nucleic Acids Research|June 30, 2026
Multivalent interactions mediate SNAIL transcription factor stimulation of the nucleosome deacetylase activity of the CoREST complexEunju Nam, Manuel Osorio Valeriano, Zhipeng A Wang, et al.Journal of the American Chemical Society|April 3, 2020
Minimalistic Principles for Designing Small Molecules with Multiple Reactivities against Pathological Factors in DementiaMingeun Kim, Juhye Kang, Misun Lee, et al.Nature Chemical Biology|July 4, 2024
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1Kwangwoon Lee, Marco Barone, Amanda L Waterbury, et al.Biorxiv : the Preprint Server for Biology|October 7, 2024
A circular engineered sortase for interrogating histone H3 in chromatinSamuel D Whedon, Kwangwoon Lee, Zhipeng A Wang, et al.Journal of the American Chemical Society|November 25, 2024
Circular Engineered Sortase for Interrogating Histone H3 in ChromatinSamuel D Whedon, Kwangwoon Lee, Zhipeng A Wang, et al.Biorxiv : the Preprint Server for Biology|May 27, 2024
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor ComplexesXiaowen Xie, Olivia Zhang, Megan J R Yeo, et al.Nature|February 12, 2025
Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutationsXiaowen Xie, Olivia Zhang, Megan J R Yeo, et al.JCI Insight|December 9, 2025
CoREST complex inhibition alters RNA splicing to promote neoantigen expression and enhance tumor immunityRobert J Fisher, Kihyun Park, Kwangwoon Lee, et al.Biorxiv : the Preprint Server for Biology|May 27, 2024
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 ComplexesMegan Jr Yeo, Olivia Zhang, Xiaowen Xie, et al.Nature|February 12, 2025
UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressorsMegan J R Yeo, Olivia Zhang, Xiaowen Xie, et al.Pageof 3