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Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|March 18, 2025
Two concurrent mechanisms are responsible for the I<sub>Na</sub> increase produced by dapagliflozin and empagliflozin in healthy and heart failure cardiomyocytesJosu Rapún, Sara Pérez-Martín, Anabel Cámara-Checa, et al.European Heart Journal. Cardiovascular Pharmacotherapy|January 29, 2022
Facing the challenge of polypharmacy when prescribing for older people with cardiovascular disease. A review by the European Society of Cardiology Working Group on Cardiovascular PharmacotherapyJuan Tamargo, Keld Per Kjeldsen, Eva Delpón, et al.Scientific Reports|July 3, 2020
The p.P888L SAP97 polymorphism increases the transient outward current (I<sub>to,f</sub>) and abbreviates the action potential duration and the QT intervalDavid Tinaquero, Teresa Crespo-García, Raquel G Utrilla, et al.International Journal of Molecular Sciences|May 11, 2024
Variable Penetrance and Expressivity of a Rare Pore Loss-of-Function Mutation (p.L889V) of Nav1.5 Channels in Three Spanish FamiliesMaría Gallego-Delgado, Anabel Cámara-Checa, Marcos Rubio-Alarcón, et al.Revista Espanola De Cardiologia (English Ed.)|October 3, 2020
A rare HCN4 variant with combined sinus bradycardia, left atrial dilatation, and hypertrabeculation/left ventricular noncompaction phenotypeMarta Alonso-Fernández-Gatta, María Gallego-Delgado, Ricardo Caballero, et al.Cardiovascular Research|February 12, 2021
Tbx5 variants disrupt Nav1.5 function differently in patients diagnosed with Brugada or Long QT SyndromePaloma Nieto-Marín, David Tinaquero, Raquel G Utrilla, et al.Proceedings of the National Academy of Sciences of the United States of America|January 5, 2017
Tbx20 controls the expression of the KCNH2 gene and of hERG channelsRicardo Caballero, Raquel G Utrilla, Irene Amorós, et al.Heart Rhythm|September 7, 2010
Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac deathElena Burashnikov, Ryan Pfeiffer, Héctor Barajas-Martinez, et al.JCI Insight|September 21, 2018
Brugada syndrome trafficking-defective Nav1.5 channels can trap cardiac Kir2.1/2.2 channelsMarta Pérez-Hernández, Marcos Matamoros, Silvia Alfayate, et al.Circulation Research|March 9, 2018
Cardiac Kir2.1 and Na<sub>V</sub>1.5 Channels Traffic Together to the Sarcolemma to Control ExcitabilityDaniela Ponce-Balbuena, Guadalupe Guerrero-Serna, Carmen R Valdivia, et al.Pageof 9