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Bioorganic & Medicinal Chemistry Letters|April 18, 2021
Discovery of a new series of PI3K-δ inhibitors from Virtual ScreeningXavier Fradera, Qiaolin Deng, Abdelganhi Achab, et al.ACS Medicinal Chemistry Letters|August 18, 2022
Discovery of MK-1462: GLP-1 and Glucagon Receptor Dual Agonist for the Treatment of Obesity and DiabetesAnandan Palani, Andrea R Nawrocki, Federica Orvieto, et al.Cell Metabolism|September 30, 2021
Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identityJorge C Correia, Yildiz Kelahmetoglu, Paulo R Jannig, et al.Bioorganic & Medicinal Chemistry Letters|August 18, 2009
Discovery of 3,3-disubstituted piperidine-derived trisubstituted ureas as highly potent soluble epoxide hydrolase inhibitorsHong C Shen, Fa-Xiang Ding, Qiaolin Deng, et al.Cell Reports. Medicine|April 17, 2024
The gonadal niche safeguards human fetal germline cell development following maternal SARS-CoV-2 infectionShijun Shen, Mengting Wang, Xiaocui Li, et al.Bioorganic & Medicinal Chemistry Letters|November 22, 2007
Discovery of orally bioavailable and novel urea agonists of the high affinity niacin receptor GPR109AHong C Shen, Michael J Szymonifka, Divya Kharbanda, et al.Journal of Medicinal Chemistry|November 21, 2024
Discovery of Potent, Highly Selective, and Efficacious SMARCA2 DegradersZhenwu Li, Lalgudi S Harikrishnan, Guozhang Xu, et al.Nature Medicine|December 4, 2019
Prenatal androgen exposure and transgenerational susceptibility to polycystic ovary syndromeSanjiv Risal, Yu Pei, Haojiang Lu, et al.Nature Immunology|April 18, 2018
Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signalingHarald Lund, Melanie Pieber, Roham Parsa, et al.Cell Reports. Medicine|April 23, 2025
CD47-blocking antibody confers metabolic benefits against obesityYajuan Su, Jingyu Sun, Xiaobo Li, et al.Pageof 14