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Bioorganic & Medicinal Chemistry Letters
|
October 27, 2015
Macrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE)
Kenneth M Boy, Jason M Guernon, Yong-Jin Wu, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
May 19, 2016
The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
Holly D Soares, Maciej Gasior, Jeremy H Toyn, et al.
Plos One
|
May 2, 2015
Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models
Sethu Sankaranarayanan, Donna M Barten, Laurel Vana, et al.
Journal of Medicinal Chemistry
|
October 4, 2012
Acyl guanidine inhibitors of β-secretase (BACE-1): optimization of a micromolar hit to a nanomolar lead via iterative solid- and solution-phase library synthesis
Samuel W Gerritz, Weixu Zhai, Shuhao Shi, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
May 25, 2012
Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027
Donna M Barten, Patrizia Fanara, Cathy Andorfer, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
May 24, 2008
P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice
Jere E Meredith, Lorin A Thompson, Jeremy H Toyn, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor
Kevin W Gillman, John E Starrett, Michael F Parker, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 17, 2010
Synthesis and SAR of indole-and 7-azaindole-1,3-dicarboxamide hydroxyethylamine inhibitors of BACE-1
Lawrence R Marcin, Mendi A Higgins, F Christopher Zusi, et al.
Molecular Cancer Therapeutics
|
May 18, 2005
Matrix metalloproteinase-activated doxorubicin prodrugs inhibit HT1080 xenograft growth better than doxorubicin with less toxicity
Charles F Albright, Nilsa Graciani, Wei Han, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 7, 2011
Synthesis and in vivo evaluation of cyclic diaminopropane BACE-1 inhibitors
Lorin A Thompson, Jianliang Shi, Carl P Decicco, et al.
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Showing results (111-120 of 131) with videos related to
Sort By:
Page
of 14
Bioorganic & Medicinal Chemistry Letters
|
October 27, 2015
Macrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE)
Kenneth M Boy, Jason M Guernon, Yong-Jin Wu, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
May 19, 2016
The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
Holly D Soares, Maciej Gasior, Jeremy H Toyn, et al.
Plos One
|
May 2, 2015
Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models
Sethu Sankaranarayanan, Donna M Barten, Laurel Vana, et al.
Journal of Medicinal Chemistry
|
October 4, 2012
Acyl guanidine inhibitors of β-secretase (BACE-1): optimization of a micromolar hit to a nanomolar lead via iterative solid- and solution-phase library synthesis
Samuel W Gerritz, Weixu Zhai, Shuhao Shi, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
May 25, 2012
Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027
Donna M Barten, Patrizia Fanara, Cathy Andorfer, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
May 24, 2008
P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice
Jere E Meredith, Lorin A Thompson, Jeremy H Toyn, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor
Kevin W Gillman, John E Starrett, Michael F Parker, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 17, 2010
Synthesis and SAR of indole-and 7-azaindole-1,3-dicarboxamide hydroxyethylamine inhibitors of BACE-1
Lawrence R Marcin, Mendi A Higgins, F Christopher Zusi, et al.
Molecular Cancer Therapeutics
|
May 18, 2005
Matrix metalloproteinase-activated doxorubicin prodrugs inhibit HT1080 xenograft growth better than doxorubicin with less toxicity
Charles F Albright, Nilsa Graciani, Wei Han, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 7, 2011
Synthesis and in vivo evaluation of cyclic diaminopropane BACE-1 inhibitors
Lorin A Thompson, Jianliang Shi, Carl P Decicco, et al.
Page
of 14