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F Blake

Showing results (121-130 of 141) with videos related to

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Journal of Medicinal Chemistry|May 27, 2016
Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical DevelopmentJames F Blake, Michael Burkard, Jocelyn Chan, et al.
Journal of Medicinal Chemistry|September 1, 2012
Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumorsJames F Blake, Rui Xu, Josef R Bencsik, et al.
ACS Medicinal Chemistry Letters|January 8, 2019
Discovery of Tetrahydropyridopyrimidines as Irreversible Covalent Inhibitors of KRAS-G12C with In Vivo ActivityJay B Fell, John P Fischer, Brian R Baer, et al.
Science Advances|June 9, 2018
Clay mineral diversity and abundance in sedimentary rocks of Gale crater, MarsThomas F Bristow, Elizabeth B Rampe, Cherie N Achilles, et al.
Bioorganic & Medicinal Chemistry Letters|August 28, 2009
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxidesJavier de Vicente, Robert T Hendricks, David B Smith, et al.
The American Mineralogist|August 12, 2017
The origin and implications of clay minerals from Yellowknife Bay, Gale crater, MarsThomas F Bristow, David L Bish, David T Vaniman, et al.
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer|January 29, 2020
RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven MalignanciesBenjamin J Solomon, Lavinia Tan, Jessica J Lin, et al.
Science (New York, N.Y.)|May 28, 2026
Hematite is a mineralogical marker of ancient climate change on MarsMarek Szczerba, Tanya S Peretyazhko, Elizabeth B Rampe, et al.
Bioorganic & Medicinal Chemistry Letters|August 25, 2009
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: synthesis and optimization studies of benzothiazine-substituted tetramic acidsJavier de Vicente, Robert T Hendricks, David B Smith, et al.
Bioorganic & Medicinal Chemistry Letters|May 22, 2009
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure-activity relationships of benzothiazine-substituted quinolinedionesJavier de Vicente, Robert T Hendricks, David B Smith, et al.
Pageof 15

Showing results (121-130 of 141) with videos related to

Sort By:
Pageof 15
Journal of Medicinal Chemistry|May 27, 2016
Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical DevelopmentJames F Blake, Michael Burkard, Jocelyn Chan, et al.
Journal of Medicinal Chemistry|September 1, 2012
Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumorsJames F Blake, Rui Xu, Josef R Bencsik, et al.
ACS Medicinal Chemistry Letters|January 8, 2019
Discovery of Tetrahydropyridopyrimidines as Irreversible Covalent Inhibitors of KRAS-G12C with In Vivo ActivityJay B Fell, John P Fischer, Brian R Baer, et al.
Science Advances|June 9, 2018
Clay mineral diversity and abundance in sedimentary rocks of Gale crater, MarsThomas F Bristow, Elizabeth B Rampe, Cherie N Achilles, et al.
Bioorganic & Medicinal Chemistry Letters|August 28, 2009
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxidesJavier de Vicente, Robert T Hendricks, David B Smith, et al.
The American Mineralogist|August 12, 2017
The origin and implications of clay minerals from Yellowknife Bay, Gale crater, MarsThomas F Bristow, David L Bish, David T Vaniman, et al.
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer|January 29, 2020
RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven MalignanciesBenjamin J Solomon, Lavinia Tan, Jessica J Lin, et al.
Science (New York, N.Y.)|May 28, 2026
Hematite is a mineralogical marker of ancient climate change on MarsMarek Szczerba, Tanya S Peretyazhko, Elizabeth B Rampe, et al.
Bioorganic & Medicinal Chemistry Letters|August 25, 2009
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: synthesis and optimization studies of benzothiazine-substituted tetramic acidsJavier de Vicente, Robert T Hendricks, David B Smith, et al.
Bioorganic & Medicinal Chemistry Letters|May 22, 2009
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure-activity relationships of benzothiazine-substituted quinolinedionesJavier de Vicente, Robert T Hendricks, David B Smith, et al.
Pageof 15