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Protein Expression and Purification|October 17, 2012
Unexpected mucin-type O-glycosylation and host-specific N-glycosylation of human recombinant interleukin-17A expressed in a human kidney cell lineKieran F Geoghegan, Xi Song, Lise R Hoth, et al.
Nature|November 16, 1989
X-ray analysis of HIV-1 proteinase at 2.7 A resolution confirms structural homology among retroviral enzymesR Lapatto, T Blundell, A Hemmings, et al.
The Journal of Clinical Investigation|February 1, 1996
Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilageP G Mitchell, H A Magna, L M Reeves, et al.
Protein Expression and Purification|June 11, 2005
Phosphorylation of serine residues in histidine-tag sequences attached to recombinant protein kinases: a cause of heterogeneity in mass and complications in functionPing Du, Pat Loulakis, Chun Luo, et al.
ACS Chemical Biology|October 9, 2014
Chemoproteomics demonstrates target engagement and exquisite selectivity of the clinical phosphodiesterase 10A inhibitor MP-10 in its native environmentJan-Philip Schülke, Laura A McAllister, Kieran F Geoghegan, et al.
Biochemical and Biophysical Research Communications|December 29, 1989
Crystallizable HIV-1 protease derived from expression of the viral pol gene in Escherichia coliD E Danley, K F Geoghegan, K G Scheld, et al.
Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA|July 9, 2011
Risedronate in adults with osteogenesis imperfecta type I: increased bone mineral density and decreased bone turnover, but high fracture rate persistsL A Bradbury, S Barlow, F Geoghegan, et al.
Protein Expression and Purification|May 11, 2010
Escherichia coli expression, purification and characterization of functional full-length recombinant alpha2beta2gamma3 heterotrimeric complex of human AMP-activated protein kinaseFrancis Rajamohan, Melissa S Harris, Richard K Frisbie, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 31, 2012
Selective mechanism-based inactivation of CYP3A4 by CYP3cide (PF-04981517) and its utility as an in vitro tool for delineating the relative roles of CYP3A4 versus CYP3A5 in the metabolism of drugsRobert L Walsky, R Scott Obach, Ruth Hyland, et al.
Journal of Neurochemistry|October 15, 2013
Phosphoproteomic evaluation of pharmacological inhibition of leucine-rich repeat kinase 2 reveals significant off-target effects of LRRK-2-IN-1Gregory C Luerman, Chuong Nguyen, Harry Samaroo, et al.
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