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ACS Medicinal Chemistry Letters
|
February 21, 2015
An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities
Yuan Cheng, James Brown, Ted C Judd, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 25, 2005
Novel ketal ligands for the glucocorticoid receptor: in vitro and in vivo activity
Cameron J Smith, Amjad Ali, James M Balkovec, et al.
Journal of Medicinal Chemistry
|
February 19, 2008
Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity
Matthew W Martin, John Newcomb, Joseph J Nunes, et al.
Journal of Medicinal Chemistry
|
March 8, 2008
Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors
Matthew M Weiss, Jean-Christophe Harmange, Anthony J Polverino, et al.
Journal of Medicinal Chemistry
|
March 8, 2008
Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation
Jean-Christophe Harmange, Matthew M Weiss, Julie Germain, et al.
Journal of Medicinal Chemistry
|
August 6, 2010
Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor
Victor J Cee, Laurie B Schenkel, Brian L Hodous, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 24, 2015
Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer's disease
Jian Jeffrey Chen, Qingyian Liu, Chester Yuan, et al.
Journal of Medicinal Chemistry
|
March 7, 2008
Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation
Erin F DiMauro, John Newcomb, Joseph J Nunes, et al.
Journal of Medicinal Chemistry
|
April 4, 2012
Design and preparation of a potent series of hydroxyethylamine containing β-secretase inhibitors that demonstrate robust reduction of central β-amyloid
Matthew M Weiss, Toni Williamson, Safura Babu-Khan, et al.
Journal of Medicinal Chemistry
|
September 15, 2006
Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity
Erin F DiMauro, John Newcomb, Joseph J Nunes, et al.
Page
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Search research articles
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Showing results (141-150 of 152) with videos related to
Sort By:
Page
of 16
ACS Medicinal Chemistry Letters
|
February 21, 2015
An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities
Yuan Cheng, James Brown, Ted C Judd, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 25, 2005
Novel ketal ligands for the glucocorticoid receptor: in vitro and in vivo activity
Cameron J Smith, Amjad Ali, James M Balkovec, et al.
Journal of Medicinal Chemistry
|
February 19, 2008
Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity
Matthew W Martin, John Newcomb, Joseph J Nunes, et al.
Journal of Medicinal Chemistry
|
March 8, 2008
Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors
Matthew M Weiss, Jean-Christophe Harmange, Anthony J Polverino, et al.
Journal of Medicinal Chemistry
|
March 8, 2008
Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation
Jean-Christophe Harmange, Matthew M Weiss, Julie Germain, et al.
Journal of Medicinal Chemistry
|
August 6, 2010
Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor
Victor J Cee, Laurie B Schenkel, Brian L Hodous, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 24, 2015
Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer's disease
Jian Jeffrey Chen, Qingyian Liu, Chester Yuan, et al.
Journal of Medicinal Chemistry
|
March 7, 2008
Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation
Erin F DiMauro, John Newcomb, Joseph J Nunes, et al.
Journal of Medicinal Chemistry
|
April 4, 2012
Design and preparation of a potent series of hydroxyethylamine containing β-secretase inhibitors that demonstrate robust reduction of central β-amyloid
Matthew M Weiss, Toni Williamson, Safura Babu-Khan, et al.
Journal of Medicinal Chemistry
|
September 15, 2006
Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity
Erin F DiMauro, John Newcomb, Joseph J Nunes, et al.
Page
of 16