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Cancer Research|October 6, 2005
Rexinoid-triggered differentiation and tumor-selective apoptosis of acute myeloid leukemia by protein kinase A-mediated desubordination of retinoid X receptorLucia Altucci, Aurélie Rossin, Oliver Hirsch, et al.The Journal of Biological Chemistry|June 29, 2019
Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signalingRomain Duval, Linh-Chi Bui, Cécile Mathieu, et al.Stem Cell Reports|November 20, 2018
Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi AnemiaCarine Domenech, Loïc Maillard, Alix Rousseau, et al.Molecular Pharmacology|June 22, 2019
T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug EtoposideQing Nian, Jérémy Berthelet, Wenchao Zhang, et al.Proceedings of the National Academy of Sciences of the United States of America|November 15, 2007
RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemiaFabien Guidez, Sarah Parks, Henna Wong, et al.Communications Biology|June 20, 2024
Protein arginine methyltransferase 2 controls inflammatory signaling in acute myeloid leukemiaCamille Sauter, Thomas Morin, Fabien Guidez, et al.JCI Insight|October 29, 2024
Comprehensive analysis of mesenchymal cells reveals a dysregulated TGF-β/WNT/HOXB7 axis in patients with myelofibrosisSaravanan Ganesan, Sarah Awan-Toor, Fabien Guidez, et al.Journal of Hematology & Oncology|January 29, 2016
GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathwaysLaura Guerenne, Stéphanie Beurlet, Mohamed Said, et al.The Journal of Biological Chemistry|February 7, 2026
The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylationChristina Michail, Jérémy Berthelet, Ariel E Mechaly, et al.Nature Communications|February 3, 2023
Myelodysplastic Syndrome associated TET2 mutations affect NK cell function and genome methylationMaxime Boy, Valeria Bisio, Lin-Pierre Zhao, et al.Pageof 4