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Autophagy|December 2, 2023
Basal activity of PINK1 and PRKN in cell models and rodent brainJens O Watzlawik, Fabienne C Fiesel, Gabriella Fiorino, et al.
The EMBO Journal|November 18, 2022
LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleusZhixiao Wu, Lena A Berlemann, Verian Bader, et al.
Autophagy|July 8, 2025
Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligaseFabienne C Fiesel, Bernardo A Bustillos, Jens O Watzlawik, et al.
Autophagy|December 5, 2022
Substitution of PINK1 Gly411 modulates substrate receptivity and turnoverFabienne C Fiesel, Dominika Fričová, Caleb S Hayes, et al.
Autophagy|June 28, 2018
Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body diseaseXu Hou, Fabienne C Fiesel, Dominika Truban, et al.
Neurology|November 13, 2015
Mitochondrial targeting sequence variants of the CHCHD2 gene are a risk for Lewy body disordersKotaro Ogaki, Shunsuke Koga, Michael G Heckman, et al.
Brain : a Journal of Neurology|November 4, 2016
Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanismAndreas Puschmann, Fabienne C Fiesel, Thomas R Caulfield, et al.
Acta Neuropathologica|March 13, 2024
Role of GBA variants in Lewy body disease neuropathologyRonald L Walton, Shunsuke Koga, Alexandra I Beasley, et al.
International Journal of Molecular Sciences|July 9, 2022
Cathepsin B p.Gly284Val Variant in Parkinson's Disease PathogenesisLukasz M Milanowski, Xu Hou, Jenny M Bredenberg, et al.
Annals of Neurology|November 7, 2025
Association between Human Leukocyte Antigen Alleles and Neuropathological Outcomes in Lewy Body DiseaseMarios Gavrielatos, Michael G Heckman, Alexandra I Soto-Beasley, et al.
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