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Molecular Pharmaceutics
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June 30, 2012
QSAR modeling and data mining link Torsades de Pointes risk to the interplay of extent of metabolism, active transport, and HERG liability
Fabio Broccatelli, Raimund Mannhold, Alessio Moriconi, et al.
Molecular Pharmaceutics
|
January 10, 2012
BDDCS class prediction for new molecular entities
Fabio Broccatelli, Gabriele Cruciani, Leslie Z Benet, et al.
ACS Medicinal Chemistry Letters
|
April 22, 2022
When Cofactors Aren't X Factors: Functional Groups That Are Labile in Human Liver Microsomes in the Absence of NADPH
Matthew L Landry, Richard Trager, Fabio Broccatelli, et al.
Molecular Pharmaceutics
|
August 13, 2024
Application of Mechanistic Multiparameter Optimization and Large-Scale <i>In Vitro</i> to <i>In Vivo</i> Pharmacokinetics Correlations to Small-Molecule Therapeutic Projects
Fabio Broccatelli, Vijayabhaskar Veeravalli, Daniel Cashion, et al.
Advanced Drug Delivery Reviews
|
January 21, 2012
Improving the prediction of the brain disposition for orally administered drugs using BDDCS
Fabio Broccatelli, Caroline A Larregieu, Gabriele Cruciani, et al.
Journal of Medicinal Chemistry
|
February 24, 2011
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields
Fabio Broccatelli, Emanuele Carosati, Annalisa Neri, et al.
Journal of Medicinal Chemistry
|
August 14, 2025
Human-Focused Multiparameter Optimization Scores for Rank Ordering Compounds during Early Drug Discovery: Validation of PBPK Models Based on Clinical PK Data
Yanran Wang, Wenyi Wang, Fabio Broccatelli, et al.
Molecular Pharmaceutics
|
October 10, 2019
Correction to "Prediction of Fraction Unbound in Microsomal and Hepatocyte Incubations: A Comparison of Methods across Industry Datasets"
Susanne Winiwarter, George Chang, Prashant Desai, et al.
ACS Medicinal Chemistry Letters
|
April 17, 2024
Balanced Permeability Index: A Multiparameter Index for Improved In Vitro Permeability
Dahlia R Weiss, Javier L Baylon, Ethan D Evans, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Ligand Promiscuity between the Efflux Pumps Human P-Glycoprotein and S. aureus NorA
Jean Pierre Brincat, Fabio Broccatelli, Stefano Sabatini, et al.
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of 4
Search research articles
Search
Showing results (11-20 of 35) with videos related to
Sort By:
Page
of 4
Molecular Pharmaceutics
|
June 30, 2012
QSAR modeling and data mining link Torsades de Pointes risk to the interplay of extent of metabolism, active transport, and HERG liability
Fabio Broccatelli, Raimund Mannhold, Alessio Moriconi, et al.
Molecular Pharmaceutics
|
January 10, 2012
BDDCS class prediction for new molecular entities
Fabio Broccatelli, Gabriele Cruciani, Leslie Z Benet, et al.
ACS Medicinal Chemistry Letters
|
April 22, 2022
When Cofactors Aren't X Factors: Functional Groups That Are Labile in Human Liver Microsomes in the Absence of NADPH
Matthew L Landry, Richard Trager, Fabio Broccatelli, et al.
Molecular Pharmaceutics
|
August 13, 2024
Application of Mechanistic Multiparameter Optimization and Large-Scale <i>In Vitro</i> to <i>In Vivo</i> Pharmacokinetics Correlations to Small-Molecule Therapeutic Projects
Fabio Broccatelli, Vijayabhaskar Veeravalli, Daniel Cashion, et al.
Advanced Drug Delivery Reviews
|
January 21, 2012
Improving the prediction of the brain disposition for orally administered drugs using BDDCS
Fabio Broccatelli, Caroline A Larregieu, Gabriele Cruciani, et al.
Journal of Medicinal Chemistry
|
February 24, 2011
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields
Fabio Broccatelli, Emanuele Carosati, Annalisa Neri, et al.
Journal of Medicinal Chemistry
|
August 14, 2025
Human-Focused Multiparameter Optimization Scores for Rank Ordering Compounds during Early Drug Discovery: Validation of PBPK Models Based on Clinical PK Data
Yanran Wang, Wenyi Wang, Fabio Broccatelli, et al.
Molecular Pharmaceutics
|
October 10, 2019
Correction to "Prediction of Fraction Unbound in Microsomal and Hepatocyte Incubations: A Comparison of Methods across Industry Datasets"
Susanne Winiwarter, George Chang, Prashant Desai, et al.
ACS Medicinal Chemistry Letters
|
April 17, 2024
Balanced Permeability Index: A Multiparameter Index for Improved In Vitro Permeability
Dahlia R Weiss, Javier L Baylon, Ethan D Evans, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Ligand Promiscuity between the Efflux Pumps Human P-Glycoprotein and S. aureus NorA
Jean Pierre Brincat, Fabio Broccatelli, Stefano Sabatini, et al.
Page
of 4