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Cellular Oncology (Dordrecht, Netherlands)|August 29, 2020
Reversine exerts cytotoxic effects through multiple cell death mechanisms in acute lymphoblastic leukemiaJorge Antonio Elias Godoy Carlos, Keli Lima, Juan Luiz Coelho-Silva, et al.
Cell Death Discovery|March 25, 2026
Autophagy inhibition potentiates the antileukemic effect of FLT3 inhibitors and overcomes resistance in FLT3-ITD acute myeloid leukemiaManuela Albuquerque de Melo, Brunno Gilberto Santos de Macedo, Diego A Pereira-Martins, et al.
Stem Cells and Development|January 14, 2014
Serine protease inhibitor kunitz-type 2 is downregulated in myelodysplastic syndromes and modulates cell-cell adhesionFernanda Marconi Roversi, Matheus Rodrigues Lopes, João Agostinho Machado-Neto, et al.
Investigational New Drugs|January 11, 2022
Phenformin increases early hematopoietic progenitors in the Jak2<sup>V617F</sup> murine modelAntônio Bruno Alves-Silva, Bruna Alves Fenerich, Natasha Peixoto Fonseca, et al.
Oncotarget|January 13, 2016
IRS2 silencing increases apoptosis and potentiates the effects of ruxolitinib in JAK2V617F-positive myeloproliferative neoplasmsPaula de Melo Campos, João A Machado-Neto, Christopher A Eide, et al.
Leukemia Research|August 21, 2014
Familial systemic mastocytosis with germline KIT K509I mutation is sensitive to treatment with imatinib, dasatinib and PKC412Paula de Melo Campos, João A Machado-Neto, Renata Scopim-Ribeiro, et al.
Hematological Oncology|December 28, 2025
Metformin Downregulates the STAT Pathway and Reduces Bone Marrow Fibrosis in Primary Myelofibrosis Patients: Final Results of the Phase II FIBROMET TrialPaula de Melo Campos, Kátia Borgia Barbosa Pagnano, Fernanda Soares Niemann, et al.
Biochimica Et Biophysica Acta. Molecular Basis of Disease|November 15, 2016
Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathwayFernanda Marconi Roversi, Fernando Vieira Pericole, João Agostinho Machado-Neto, et al.
European Journal of Pharmacology|April 17, 2026
Quizartinib-induced resistance drives clonal emergence of MV4-11 cells with molecular alterations enabling multidrug antileukemic escapeLivia Bassani Lins de Miranda, Keli Lima, Diego A Pereira-Martins, et al.
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