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Journal of Alzheimer'S Disease : JAD|April 30, 2016
Alzheimer's Disease Risk Genes and Lipid RegulatorsFarida El Gaamouch, Ping Jing, Jiahong Xia, et al.
Biorxiv : the Preprint Server for Biology|June 12, 2025
TREM2 Hit Discovery Using TRIC Technology: A Proof-of-Concept High-Throughput Screening ApproachNatalie Fuchs, Katarzyna Kuncewicz, Farida El Gaamouch, et al.
SLAS Discovery : Advancing Life Sciences R & D|August 1, 2025
TREM2 hit discovery using temperature-related intensity change (TRIC) technology: A proof-of-concept high-throughput screening approachNatalie Fuchs, Katarzyna Kuncewicz, Farida El Gaamouch, et al.
Neurochemistry International|April 19, 2021
Development of grape polyphenols as multi-targeting strategies for Alzheimer's diseaseFarida El Gaamouch, Kalena Liu, Hsiao-Yun Lin, et al.
Bioorganic & Medicinal Chemistry|March 7, 2026
High-throughput fragment screening identifies a new small molecule scaffold that modulates TREM2 SignalingNatalie Fuchs, Farida El Gaamouch, Hossam Nada, et al.
Biorxiv : the Preprint Server for Biology|February 6, 2026
Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Human Alzheimer's ModelsHossam Nada, Shaoren Yuan, Farida El Gaamouch, et al.
Biorxiv : the Preprint Server for Biology|December 8, 2025
High-Throughput Fragment Screening Identifies a New Small Molecule Scaffold that Modulates TREM2 SignalingNatalie Fuchs, Farida El Gaamouch, Hossam Nada, et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|December 3, 2025
As48, a first-in-class dual-function TREM2 modulator: Receptor activation and shedding inhibitionSungwoo Cho, Farida El Gaamouch, Saurabh Upadhyay, et al.
Biorxiv : the Preprint Server for Biology|July 16, 2025
Discovery of an Achiral Small Molecule TREM2 Agonist with Improved Pharmacokinetic Profile and Validated Target EngagementShaoren Yuan, Farida El Gaamouch, Sungwoo Cho, et al.
Biorxiv : the Preprint Server for Biology|June 12, 2025
TREM2 Activation by First-in-Class Direct Small Molecule Agonists: DEL Screening, Optimization, Biophysical Validation, and Functional CharacterizationHossam Nada, Farida El Gaamouch, Sungwoo Cho, et al.
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