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Cancer Chemotherapy and Pharmacology
|
May 8, 2019
A single-center, open-label study investigating the excretion balance, pharmacokinetics, metabolism, and absolute bioavailability of a single oral dose of [<sup>14</sup>C]-labeled idasanutlin and an intravenous tracer dose of [<sup>13</sup>C]-labeled idasanutlin in a single cohort of patients with solid tumors
Zsuzsanna Pápai, Lin-Chi Chen, Daniel Da Costa, et al.
Bioanalysis
|
January 8, 2026
Streamlined neutralizing antibody assay development: overcoming serum interference, utilization of DOE and automation
Kelly Ngoc Pham, Nazneen Bano, Leonard J Rubinstein, et al.
Analytical Chemistry
|
November 6, 2020
Toward Accurate and Robust Liquid Chromatography-Mass Spectrometry-Based Quantification of Antibody Biotherapeutics in Tissues
Bo An, Ming Zhang, Jie Pu, et al.
The AAPS Journal
|
May 5, 2022
Is Incurred Sample Reanalysis (ISR) Applicable in Biomarker Assays?
Amanda Hays, Lakshmi Amaravadi, Carmen Fernandez-Metzler, et al.
Cancer Chemotherapy and Pharmacology
|
January 26, 2018
Effects of posaconazole (a strong CYP3A4 inhibitor), two new tablet formulations, and food on the pharmacokinetics of idasanutlin, an MDM2 antagonist, in patients with advanced solid tumors
John Nemunaitis, Annie Young, Samuel Ejadi, et al.
Bioanalysis
|
July 11, 2020
Clinical application of volumetric absorptive microsampling to the gefapixant development program
Brad Roadcap, Azher Hussain, Dan Dreyer, et al.
Journal of Clinical Pharmacology
|
July 28, 2018
Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib
Peter N Morcos, Yumi Cleary, Carolina Sturm-Pellanda, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
November 21, 2015
Investigating the effect of autoinduction in cynomolgus monkeys of a novel anticancer MDM2 antagonist, idasanutlin, and relevance to humans
Kelli J Glenn, Li J Yu, Micaela B Reddy, et al.
The AAPS Journal
|
August 20, 2014
Repeat analysis and incurred sample reanalysis: recommendation for best practices and harmonization from the global bioanalysis consortium harmonization team
Eric Fluhler, Faye Vazvaei, Puran Singhal, et al.
The AAPS Journal
|
May 9, 2022
Biomarker Assay Validation by Mass Spectrometry
Carmen Fernández-Metzler, Brad Ackermann, Fabio Garofolo, et al.
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Search research articles
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Showing results (11-20 of 30) with videos related to
Sort By:
Page
of 3
Cancer Chemotherapy and Pharmacology
|
May 8, 2019
A single-center, open-label study investigating the excretion balance, pharmacokinetics, metabolism, and absolute bioavailability of a single oral dose of [<sup>14</sup>C]-labeled idasanutlin and an intravenous tracer dose of [<sup>13</sup>C]-labeled idasanutlin in a single cohort of patients with solid tumors
Zsuzsanna Pápai, Lin-Chi Chen, Daniel Da Costa, et al.
Bioanalysis
|
January 8, 2026
Streamlined neutralizing antibody assay development: overcoming serum interference, utilization of DOE and automation
Kelly Ngoc Pham, Nazneen Bano, Leonard J Rubinstein, et al.
Analytical Chemistry
|
November 6, 2020
Toward Accurate and Robust Liquid Chromatography-Mass Spectrometry-Based Quantification of Antibody Biotherapeutics in Tissues
Bo An, Ming Zhang, Jie Pu, et al.
The AAPS Journal
|
May 5, 2022
Is Incurred Sample Reanalysis (ISR) Applicable in Biomarker Assays?
Amanda Hays, Lakshmi Amaravadi, Carmen Fernandez-Metzler, et al.
Cancer Chemotherapy and Pharmacology
|
January 26, 2018
Effects of posaconazole (a strong CYP3A4 inhibitor), two new tablet formulations, and food on the pharmacokinetics of idasanutlin, an MDM2 antagonist, in patients with advanced solid tumors
John Nemunaitis, Annie Young, Samuel Ejadi, et al.
Bioanalysis
|
July 11, 2020
Clinical application of volumetric absorptive microsampling to the gefapixant development program
Brad Roadcap, Azher Hussain, Dan Dreyer, et al.
Journal of Clinical Pharmacology
|
July 28, 2018
Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib
Peter N Morcos, Yumi Cleary, Carolina Sturm-Pellanda, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
November 21, 2015
Investigating the effect of autoinduction in cynomolgus monkeys of a novel anticancer MDM2 antagonist, idasanutlin, and relevance to humans
Kelli J Glenn, Li J Yu, Micaela B Reddy, et al.
The AAPS Journal
|
August 20, 2014
Repeat analysis and incurred sample reanalysis: recommendation for best practices and harmonization from the global bioanalysis consortium harmonization team
Eric Fluhler, Faye Vazvaei, Puran Singhal, et al.
The AAPS Journal
|
May 9, 2022
Biomarker Assay Validation by Mass Spectrometry
Carmen Fernández-Metzler, Brad Ackermann, Fabio Garofolo, et al.
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