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Science (New York, N.Y.)|August 10, 2019
A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignanciesSteffen Boettcher, Peter G Miller, Rohan Sharma, et al.Cancer Discovery|December 28, 2022
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in CarcinomasLisa D Cervia, Tsukasa Shibue, Ashir A Borah, et al.Molecular Cell|May 10, 2022
NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibitionYiannis Drosos, Jacquelyn A Myers, Beisi Xu, et al.Nature Communications|June 30, 2022
Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational statePeter G Miller, Murugappan Sathappa, Jamie A Moroco, et al.Cancer Discovery|May 6, 2016
Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic AllelesEejung Kim, Nina Ilic, Yashaswi Shrestha, et al.Nature Communications|July 17, 2021
Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNaseColin W Garvie, Xiaoyun Wu, Malvina Papanastasiou, et al.Cell Stem Cell|February 16, 2023
Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villagesMichael F Wells, James Nemesh, Sulagna Ghosh, et al.Nature Genetics|March 4, 2014
An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemiaBirgit Knoechel, Justine E Roderick, Kaylyn E Williamson, et al.Nature Communications|March 29, 2024
Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutantsTikvah K Hayes, Elisa Aquilanti, Nicole S Persky, et al.Cancer Cell|August 2, 2016
High-throughput Phenotyping of Lung Cancer Somatic MutationsAlice H Berger, Angela N Brooks, Xiaoyun Wu, et al.Pageof 8