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Nature Structural & Molecular Biology|October 6, 2022
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transductionJohn T Happ, Corvin D Arveseth, Jessica Bruystens, et al.
Plos Biology|April 22, 2021
Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunitsCorvin D Arveseth, John T Happ, Danielle S Hedeen, et al.
Hepatobiliary Surgery and Nutrition|August 21, 2023
LEARN algorithm: a novel option for predicting non-alcoholic steatohepatitisGang Li, Tian-Lei Zheng, Xiao-Ling Chi, et al.
Biorxiv : the Preprint Server for Biology|November 18, 2024
A Structural Mechanism for Noncanonical GPCR Signal Transduction in the Hedgehog PathwayWilliam P Steiner, Nathan Iverson, Varun Venkatakrishnan, et al.
Plos Biology|August 13, 2024
GRK2 kinases in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascadeMadison F Walker, Jingyi Zhang, William Steiner, et al.
Biorxiv : the Preprint Server for Biology|May 22, 2023
GRK2 Kinases in the Primary Cilium Initiate SMOOTHENED-PKA Signaling in the Hedgehog CascadeMadison F Walker, Jingyi Zhang, William Steiner, et al.
The Journal of Clinical Investigation|September 26, 2023
Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignanciesStephen Jun Fei Chong, Fen Zhu, Olga Dashevsky, et al.
Nature Structural & Molecular Biology|April 30, 2026
Structural mechanism for noncanonical GPCR signaling in the Hedgehog pathwayWilliam P Steiner, Nathan Iverson, Guibing Liu, et al.
Nature Communications|February 7, 2024
ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97Amir Pozner, Li Li, Shiv Prakash Verma, et al.
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