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Proceedings of the National Academy of Sciences of the United States of America|July 12, 2020
Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiencyLena J McLaughlin, Lora Stojanovic, Aksinija A Kogan, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|January 29, 2022
Phase I Clinical Trial of DNA Methyltransferase Inhibitor Decitabine and PARP Inhibitor Talazoparib Combination Therapy in Relapsed/Refractory Acute Myeloid LeukemiaMaria R Baer, Aksinija A Kogan, Søren M Bentzen, et al.Proceedings of the National Academy of Sciences of the United States of America|June 27, 2022
Activating STING1-dependent immune signaling in TP53 mutant and wild-type acute myeloid leukemiaAksinija A Kogan, Michael J Topper, Anna J Dellomo, et al.Cancer|April 14, 2026
A phase 1 study of ASTX727 plus talazoparib in patients with triple-negative or hormone resistant/HER2-negative metastatic breast cancerKathy D Miller, Alexandra Thomas, Sandra Althouse, et al.Oncotarget|September 10, 2021
Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplicationMario Scarpa, Shivani Kapoor, Eric S Tvedte, et al.Pharmaceuticals (Basel, Switzerland)|January 23, 2016
Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Resistance Proteins ABCB1 and ABCG2Rena G Lapidus, Brandon A Carter-Cooper, Mariola Sadowska, et al.Cancer Cell|May 10, 2017
CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor GenesLimin Xia, Wenjie Huang, Marina Bellani, et al.Blood|July 10, 2013
Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profileKimberly Cramer-Morales, Margaret Nieborowska-Skorska, Kara Scheibner, et al.Cancer Cell|October 12, 2016
Enhancing the Cytotoxic Effects of PARP Inhibitors with DNA Demethylating Agents - A Potential Therapy for CancerNidal E Muvarak, Khadiza Chowdhury, Limin Xia, et al.Cancer Research|September 16, 2010
Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cellsJoyce E Ohm, Prashant Mali, Leander Van Neste, et al.Pageof 5