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Journal of Cancer Research and Clinical Oncology|November 14, 2024
A novel mouse model recapitulating the MMR-defective SCLC subtype uncovers an actionable sensitivity to immune checkpoint blockadeOlta Ibruli, France Rose, Filippo Beleggia, et al.The Journal of Clinical Investigation|August 18, 2015
RAP1-mediated MEK/ERK pathway defects in Kabuki syndromeNina Bögershausen, I-Chun Tsai, Esther Pohl, et al.Nature Communications|July 29, 2017
Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemiaGero Knittel, Tim Rehkämper, Darya Korovkina, et al.Human Genetics|April 11, 2017
Heterozygous HNRNPU variants cause early onset epilepsy and severe intellectual disabilityNuria C Bramswig, Hermann-Josef Lüdecke, Fadi F Hamdan, et al.Journal of Medical Genetics|October 17, 2018
Specific combinations of biallelic POLR3A variants cause Wiedemann-Rautenstrauch syndromeStefano Paolacci, Yun Li, Emanuele Agolini, et al.Cell Reports|October 26, 2018
The Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor SuppressionAlessandro Torgovnick, Jan Michel Heger, Vasiliki Liaki, et al.American Journal of Human Genetics|December 3, 2014
Mutations in CKAP2L, the human homolog of the mouse Radmis gene, cause Filippi syndromeMuhammad Sajid Hussain, Agatino Battaglia, Sandra Szczepanski, et al.Nature Communications|December 8, 2025
ERBB2 signaling drives immune cell evasion and resistance against immunotherapy in small cell lung cancerLydia Meder, Charlotte I Orschel, Cyrielle L Bouchez, et al.Nature Communications|June 15, 2026
Oncogenic KRAS-driven type I interferon signalling primes pancreatic cancer for necroptosisSofya Tishina, Alina Dahlhaus, Marta Manik, et al.Cell|January 8, 2019
UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive TumorsRon D Jachimowicz, Filippo Beleggia, Jörg Isensee, et al.Pageof 4