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Clinical Pharmacokinetics|February 21, 2006
Role of mechanistically-based pharmacokinetic/pharmacodynamic models in drug development : a case study of a therapeutic proteinScott Marshall, Fiona Macintyre, Ian James, et al.
Pharmaceutical Research|August 4, 2005
Bridging the pharmacokinetics and pharmacodynamics of UK-279,276 across healthy volunteers and stroke patients using a mechanistically based model for target-mediated dispositionE Niclas Jonsson, Fiona Macintyre, Ian James, et al.
British Journal of Clinical Pharmacology|May 14, 2015
Evaluation of the QT effect of a combination of piperaquine and a novel anti-malarial drug candidate OZ439, for the treatment of uncomplicated malariaBorje Darpo, Georg Ferber, Peter Siegl, et al.
Clinical Pharmacology and Therapeutics|August 28, 2021
Unanticipated CNS Safety Signal in a Placebo-Controlled, Randomized Trial of Co-Administered Atovaquone-Proguanil and AmodiaquineStephan Chalon, M Farouk Chughlay, Nada Abla, et al.
Malaria Journal|December 12, 2018
A discovery and development roadmap for new endectocidal transmission-blocking agents in malariaJeremy Burrows, Hannah Slater, Fiona Macintyre, et al.
The Lancet. Infectious Diseases|October 9, 2015
Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trialAung Pyae Phyo, Podjanee Jittamala, François H Nosten, et al.
Malaria Journal|January 15, 2017
New developments in anti-malarial target candidate and product profilesJeremy N Burrows, Stephan Duparc, Winston E Gutteridge, et al.
Malaria Journal|November 3, 2018
Injectable anti-malarials revisited: discovery and development of new agents to protect against malariaFiona Macintyre, Hanu Ramachandruni, Jeremy N Burrows, et al.
Malaria Journal|April 11, 2019
African isolates show a high proportion of multiple copies of the Plasmodium falciparum plasmepsin-2 gene, a piperaquine resistance markerDidier Leroy, Fiona Macintyre, Yeka Adoke, et al.
Bioorganic & Medicinal Chemistry Letters|June 9, 2009
SAR of a series of inhaled A(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic dataSimon J Mantell, Peter T Stephenson, Sandra M Monaghan, et al.
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