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Blood|June 29, 2026
Menin-MLL inhibitors enhance JUND activity in MLLr leukemic cells contributing to tumorigenesis and therapy resistanceEzgi Ozyerli-Goknar, Sheikh Nizamuddin, Viktor Fetsch, et al.Leukemia|May 28, 2020
Prevalence and dynamics of clonal hematopoiesis caused by leukemia-associated mutations in elderly individuals without hematologic disordersDanica Midic, Jenny Rinke, Florian Perner, et al.Molecular Cell|March 4, 2022
MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscapeSarah Naomi Olsen, Laura Godfrey, James P Healy, et al.Cell Reports|October 30, 2024
NUP98 fusion proteins and KMT2A-MENIN antagonize PRC1.1 to drive gene expression in AMLEmily B Heikamp, Cynthia Martucci, Jill A Henrich, et al.Leukemia|August 9, 2025
The histone-methyltransferase DOT1L cooperates with LSD1 to control cell division in blast-phase MPNKarl Kapahnke, Thomas Plenge, Tabea Klaus, et al.Cancer Discovery|December 1, 2022
Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid LeukemiaHannah J Uckelmann, Elena L Haarer, Reina Takeda, et al.Leukemia|June 2, 2022
Histone demethylase KDM4C is a functional dependency in JAK2-mutated neoplasmsPhilipp Ernst, Tina M Schnöder, Nicolas Huber, et al.Blood|July 8, 2026
USP22 is a novel vulnerability regulating MEIS1 protein abundance and gene transcription in KMT2Ar acute leukemiaSarah Bröchtel, Constanze Schneider, Marius Müller, et al.Leukemia|October 3, 2019
The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AMLMelanie Kahl, Annamaria Brioli, Martin Bens, et al.Blood|September 28, 2021
The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AMLEmily B Heikamp, Jill A Henrich, Florian Perner, et al.Pageof 4