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The Journal of Clinical Investigation|November 15, 2011
T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in miceFlorian Wiede, Benjamin J Shields, Sock Hui Chew, et al.Diabetes|April 3, 2019
T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune ComorbiditiesFlorian Wiede, Thomas C Brodnicki, Pei Kee Goh, et al.Plos One|May 17, 2012
Strain-dependent differences in bone development, myeloid hyperplasia, morbidity and mortality in ptpn2-deficient miceFlorian Wiede, Sock Hui Chew, Catherine van Vliet, et al.Diabetologia|October 24, 2014
Pancreatic T cell protein-tyrosine phosphatase deficiency affects beta cell function in miceYannan Xi, Siming Liu, Ahmed Bettaieb, et al.Biorxiv : the Preprint Server for Biology|July 3, 2023
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunityShuwei Liang, Eric Tran, Xin Du, et al.Science Advances|February 23, 2022
PTPN2 elicits cell autonomous and non-cell autonomous effects on antitumor immunity in triple-negative breast cancerPei Kee Goh, Florian Wiede, Mara N Zeissig, et al.Cell Reports|July 30, 2020
PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T CellsMarkus Flosbach, Susanne G Oberle, Stefanie Scherer, et al.Angewandte Chemie (International Ed. in English)|March 27, 2023
Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T-Cell Protein Tyrosine Phosphatase for Cancer ImmunotherapyJiajun Dong, Jinmin Miao, Yiming Miao, et al.Nature Communications|July 27, 2023
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunityShuwei Liang, Eric Tran, Xin Du, et al.The Journal of Clinical Investigation|December 7, 2023
Mitochondria- and NOX4-dependent antioxidant defense mitigates progression to nonalcoholic steatohepatitis in obesitySpencer Greatorex, Supreet Kaur, Chrysovalantou E Xirouchaki, et al.Pageof 5