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European Journal of Medicinal Chemistry
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January 15, 2026
Structure-based virtual screening of ultra-large chemical spaces: Advances and pitfalls
François Sindt, Didier Rognan
Journal of Chemical Information and Modeling
|
May 22, 2025
On the Difficulty to Rescore Hits from Ultralarge Docking Screens
François Sindt, Guillaume Bret, Didier Rognan
Journal of Chemical Information and Modeling
|
January 27, 2026
Assessing Boltz-2 Performance for the Binding Classification of Docking Hits
Guillaume Bret, François Sindt, Didier Rognan
Journal of Chemical Information and Modeling
|
January 16, 2025
Active Learning to Select the Most Suitable Reagents and One-Step Organic Chemistry Reactions for Prioritizing Target-Specific Hits from Ultralarge Chemical Spaces
Vladimir Kozyrev, François Sindt, Didier Rognan
ACS Central Science
|
April 1, 2024
Protein Structure-Based Organic Chemistry-Driven Ligand Design from Ultralarge Chemical Spaces
François Sindt, Anthony Seyller, Merveille Eguida, et al.
Biorxiv : the Preprint Server for Biology
|
August 20, 2025
Structure-Guided Discovery of CHI3L1 Inhibitors from Ultralarge Chemical Spaces for Glioblastoma Therapy
Baljit Kaur, François Sindt, Longfei Zhang, et al.
ACS Omega
|
January 19, 2026
Structure-Guided Discovery of CHI3L1 Inhibitors from Ultralarge Chemical Spaces for Glioblastoma Therapy
Baljit Kaur, François Sindt, Longfei Zhang, et al.
Journal of Chemical Information and Modeling
|
June 25, 2024
Subpocket Similarity-Based Hit Identification for Challenging Targets: Application to the WDR Domain of LRRK2
Merveille Eguida, Guillaume Bret, François Sindt, et al.
Journal of Chemical Information and Modeling
|
January 21, 2026
CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2
Oleksandra Herasymenko, Madhushika Silva, Galen J Correy, et al.
Journal of Chemical Information and Modeling
|
November 5, 2024
CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein
Fengling Li, Suzanne Ackloo, Cheryl H Arrowsmith, et al.
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Search research articles
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Showing results (1-10 of 10) with videos related to
Sort By:
Page
of 1
European Journal of Medicinal Chemistry
|
January 15, 2026
Structure-based virtual screening of ultra-large chemical spaces: Advances and pitfalls
François Sindt, Didier Rognan
Journal of Chemical Information and Modeling
|
May 22, 2025
On the Difficulty to Rescore Hits from Ultralarge Docking Screens
François Sindt, Guillaume Bret, Didier Rognan
Journal of Chemical Information and Modeling
|
January 27, 2026
Assessing Boltz-2 Performance for the Binding Classification of Docking Hits
Guillaume Bret, François Sindt, Didier Rognan
Journal of Chemical Information and Modeling
|
January 16, 2025
Active Learning to Select the Most Suitable Reagents and One-Step Organic Chemistry Reactions for Prioritizing Target-Specific Hits from Ultralarge Chemical Spaces
Vladimir Kozyrev, François Sindt, Didier Rognan
ACS Central Science
|
April 1, 2024
Protein Structure-Based Organic Chemistry-Driven Ligand Design from Ultralarge Chemical Spaces
François Sindt, Anthony Seyller, Merveille Eguida, et al.
Biorxiv : the Preprint Server for Biology
|
August 20, 2025
Structure-Guided Discovery of CHI3L1 Inhibitors from Ultralarge Chemical Spaces for Glioblastoma Therapy
Baljit Kaur, François Sindt, Longfei Zhang, et al.
ACS Omega
|
January 19, 2026
Structure-Guided Discovery of CHI3L1 Inhibitors from Ultralarge Chemical Spaces for Glioblastoma Therapy
Baljit Kaur, François Sindt, Longfei Zhang, et al.
Journal of Chemical Information and Modeling
|
June 25, 2024
Subpocket Similarity-Based Hit Identification for Challenging Targets: Application to the WDR Domain of LRRK2
Merveille Eguida, Guillaume Bret, François Sindt, et al.
Journal of Chemical Information and Modeling
|
January 21, 2026
CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2
Oleksandra Herasymenko, Madhushika Silva, Galen J Correy, et al.
Journal of Chemical Information and Modeling
|
November 5, 2024
CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein
Fengling Li, Suzanne Ackloo, Cheryl H Arrowsmith, et al.
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