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Oral Oncology|January 14, 2024
Evolutionary dynamics of tipifarnib in HRAS mutated head and neck squamous cell carcinomaSankar Jagadeeshan, Kushal Suryamohan, Nara Shin, et al.Nature Communications|June 27, 2024
Farnesyltransferase inhibition overcomes oncogene-addicted non-small cell lung cancer adaptive resistance to targeted therapiesSarah Figarol, Célia Delahaye, Rémi Gence, et al.Cancer Research|June 20, 2023
Tipifarnib Potentiates the Antitumor Effects of PI3Kα Inhibition in PIK3CA- and HRAS-Dysregulated HNSCC via Convergent Inhibition of mTOR ActivityAlison E Smith, Stacia Chan, Zhiyong Wang, et al.Cancer Research|February 8, 2023
Mutated HRAS Activates YAP1-AXL Signaling to Drive Metastasis of Head and Neck CancerSankar Jagadeeshan, Manu Prasad, Mai Badarni, et al.Blood|March 18, 2026
Discovery and preclinical activity of the menin-KMT2A inhibitor ziftomenib in acute leukemia modelsHongzhi Miao, Tao Wu, Trupta Purohit, et al.The Journal of Clinical Investigation|December 20, 2019
Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemiaSzymon Klossowski, Hongzhi Miao, Katarzyna Kempinska, et al.Nature Genetics|September 3, 2024
In vivo CRISPR screens identify a dual function of MEN1 in regulating tumor-microenvironment interactionsPeiran Su, Yin Liu, Tianyi Chen, et al.Pageof 4