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Cell|May 13, 2026
Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effectsSriram Pendyala, Katie Partington, Nicholas Bradley, et al.
Nature Biotechnology|May 9, 2007
Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegansDenis Dupuy, Nicolas Bertin, César A Hidalgo, et al.
The Journal of Clinical Investigation|September 5, 2008
Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injuryGregory D Lewis, Ru Wei, Emerson Liu, et al.
Circulation|July 12, 2026
Scaled Multidimensional Assays of Variant Effect Identify Sequence-Function Relationships in Hypertrophic CardiomyopathyYuta Yamamoto, Kaiser Chua, David Staudt, et al.
Cell|October 1, 2024
Pervasive mislocalization of pathogenic coding variants underlying human disordersJessica Lacoste, Marzieh Haghighi, Shahan Haider, et al.
Molecular Systems Biology|April 24, 2016
An inter-species protein-protein interaction network across vast evolutionary distanceQuan Zhong, Samuel J Pevzner, Tong Hao, et al.
Nature Communications|April 12, 2014
Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autismRoser Corominas, Xinping Yang, Guan Ning Lin, et al.
Human Genetics|August 7, 2024
Assessing predictions on fitness effects of missense variants in HMBS in CAGI6Jing Zhang, Lisa Kinch, Panagiotis Katsonis, et al.
Molecular Cancer Therapeutics|December 4, 2020
AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, SelumetinibVikki Flemington, Emma J Davies, David Robinson, et al.
Communications Biology|January 26, 2021
Design and optimisation of dendrimer-conjugated Bcl-2/xL inhibitor, AZD0466, with improved therapeutic index for cancer therapyClaire M Patterson, Srividya B Balachander, Iain Grant, et al.
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