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Journal of Medicinal Chemistry|November 24, 2005
2-(Quinazolin-4-ylamino)-[1,4]benzoquinones as covalent-binding, irreversible inhibitors of the kinase domain of vascular endothelial growth factor receptor-2Allan Wissner, M Brawner Floyd, Bernard D Johnson, et al.Cancer Biology & Therapy|January 24, 2004
Targeting vascular and avascular compartments of tumors with C. novyi-NT and anti-microtubule agentsLong H Dang, Chetan Bettegowda, Nishant Agrawal, et al.ACS Medicinal Chemistry Letters|November 25, 2016
Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC PayloadsCarolyn A Leverett, Sai Chetan K Sukuru, Beth C Vetelino, et al.The AAPS Journal|April 26, 2017
Site Selection: a Case Study in the Identification of Optimal Cysteine Engineered Antibody Drug ConjugatesL Nathan Tumey, Fengping Li, Brian Rago, et al.Cancer Research|April 19, 2003
HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivoFrank Loganzo, Carolyn M Discafani, Tami Annable, et al.Journal of Medicinal Chemistry|September 3, 2004
Synthesis and biological activity of analogues of the antimicrotubule agent N,beta,beta-trimethyl-L-phenylalanyl-N(1)-[(1S,2E)-3-carboxy-1-isopropylbut-2-enyl]- N(1),3-dimethyl-L-valinamide (HTI-286)Arie Zask, Gary Birnberg, Katherine Cheung, et al.Bioconjugate Chemistry|July 15, 2016
Natural Product Splicing Inhibitors: A New Class of Antibody-Drug Conjugate (ADC) PayloadsSujiet Puthenveetil, Frank Loganzo, Haiyin He, et al.Bioconjugate Chemistry|December 14, 2018
Natural Product Bis-Intercalator Depsipeptides as a New Class of Payloads for Antibody-Drug ConjugatesAnokha S Ratnayake, Li-Ping Chang, L Nathan Tumey, et al.Journal of Medicinal Chemistry|November 29, 2014
Discovery of cytotoxic dolastatin 10 analogues with N-terminal modificationsAndreas Maderna, Matthew Doroski, Chakrapani Subramanyam, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|November 5, 2020
Development of Highly Optimized Antibody-Drug Conjugates against CD33 and CD123 for Acute Myeloid LeukemiaYoon-Chi Han, Jennifer Kahler, Nicole Piché-Nicholas, et al.Pageof 5