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Frontiers in Neuroscience|July 18, 2019
Nerve Growth Factor Pathobiology During the Progression of Alzheimer's DiseaseElliott J Mufson, Scott E Counts, Stephen D Ginsberg, et al.Neuropharmacology|June 24, 2016
A small molecule TrkB/TrkC neurotrophin receptor co-activator with distinctive effects on neuronal survival and process outgrowthTao Yang, Stephen M Massa, Kevin C Tran, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|January 11, 2013
Oral administration of a small molecule targeted to block proNGF binding to p75 promotes myelin sparing and functional recovery after spinal cord injuryChhavy Tep, Tae Hee Lim, Pyung On Ko, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|May 19, 2006
Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced deathStephen M Massa, Youmei Xie, Tao Yang, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|August 28, 2009
The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivoJuliet K Knowles, Jayakumar Rajadas, Thuy-Vi V Nguyen, et al.Human Molecular Genetics|February 8, 2017
A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD miceDanielle A Simmons, Nadia P Belichenko, Ellen C Ford, et al.Nature Medicine|May 17, 2024
p75 neurotrophin receptor modulation in mild to moderate Alzheimer disease: a randomized, placebo-controlled phase 2a trialHayley R C Shanks, Kewei Chen, Eric M Reiman, et al.Proceedings of the National Academy of Sciences of the United States of America|August 10, 2005
Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse modelTrent Nguyen, Aaron Hamby, Stephen M MassaJournal of Alzheimer'S Disease : JAD|June 6, 2014
Small molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AβPP(L/S) transgenic miceThuy-Vi V Nguyen, Lin Shen, Lilith Vander Griend, et al.BMC Neuroscience|October 22, 2010
The p75 neurotrophin receptor is expressed by adult mouse dentate progenitor cells and regulates neuronal and non-neuronal cell genesisRamon O Bernabeu, Frank M LongoPageof 12