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British Journal of Pharmacology|May 12, 2023
Identification and characterization of the new generation soluble guanylate cyclase stimulator BAY-747 designed for the treatment of resistant hypertensionFrank Wunder, Johannes-Peter Stasch, Andreas Knorr, et al.
Plos Computational Biology|January 26, 2010
A multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homologyJacob D Durrant, Rommie E Amaro, Lei Xie, et al.
Development (Cambridge, England)|September 4, 2014
Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytesJeremy R Egbert, Leia C Shuhaibar, Aaron B Edmund, et al.
The Journal of Biological Chemistry|April 2, 2011
Chemosensory Ca2+ dynamics correlate with diverse behavioral phenotypes in human spermThomas Veitinger, Jeffrey R Riffell, Sophie Veitinger, et al.
British Journal of Pharmacology|June 28, 2002
NO- and haem-independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principleJohannes-Peter Stasch, Peter Schmidt, Cristina Alonso-Alija, et al.
Journal of Medicinal Chemistry|March 18, 2023
BAY-6096: A Potent, Selective, and Highly Water-Soluble Adrenergic α2B AntagonistDaniel Meibom, Jutta Meyer, Clemens-Jeremias von Buehler, et al.
Chemmedchem|March 6, 2009
Discovery of riociguat (BAY 63-2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertensionJoachim Mittendorf, Stefan Weigand, Cristina Alonso-Alija, et al.
Biology of Reproduction|March 25, 2016
Luteinizing Hormone Causes Phosphorylation and Activation of the cGMP Phosphodiesterase PDE5 in Rat Ovarian Follicles, Contributing, Together with PDE1 Activity, to the Resumption of MeiosisJeremy R Egbert, Tracy F Uliasz, Leia C Shuhaibar, et al.
Journal of Medicinal Chemistry|December 8, 2022
BAY-7081: A Potent, Selective, and Orally Bioavailable Cyanopyridone-Based PDE9A InhibitorDaniel Meibom, Sina Micus, Anna Lena Andreevski, et al.
Nature Cardiovascular Research|July 24, 2023
Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammationCarina Mauersberger, Hendrik B Sager, Jana Wobst, et al.
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